Puromycin dihydrochloride | CAS 58-58-2

Element: dihydrochloride puromycin

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C-S » Chemicals » puromycin-dihydrochloride-PX68296

Identification

Puromycin dihydrochloride

CAS:

58-58-2

EINECS:

200-387-8

Molecular Formula:

C₂₂H₂₉ N₇ O₅ . 2 Cl H

MDL:

MFCD00012691

SMILES:

CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@@H](CC4=CC=C(C=C4)OC)N)O.Cl.Cl

Synonym:

pdh ; stylomycinhydrochloride ; puromycindihyrochloride ; l-2hc ; puromycin hydrochloride ; p 638dihydrochloride ; puromycinhydrochloride ; adenosine,3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-n,n-dimethyl-,dihydrochloride, (s)- ; adenosine,3'-[[(2s)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-n,n-dimethyl-,hydrochloride (1:2) ; cl 16536 ; cl 13900 dihydrochloride ; stylomycin dihydrochloride ; puromycin dihydrochloride ; cl 16,536 ; puromycin dihydrochlorid ; 3'-(l-a-amino-p-methoxyhydrocinnamamido)-3'-deoxy-n,n-dimethyladenosinedihydrochloride ; puromycin 2hydrochloride ; puromycin ; adenosine,3'-(a-amino-p-methoxyhydrocinnamamido)-3'-deoxy-n,n-dimethyl-,dihydrochloride, l- (8ci) ; nsc 3055 ; adenosine,3'-[[(2s)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-n,n-dimethyl-,dihydrochloride (9ci) ; puromycin 2hcl

Description

Puromycin is an aminonuclease antibiotic used for selection and maintenance of cell lines expressing a transfected pac gene, whose product, puromycin-N-acetyl-transferase, inactivates puromycin via acetylation.
Puromycin is an antibiotic substance produced by the soil actinomycete Streptomyces alboniger which induces apoptosis in cells by interfering with RNA function, leading to inhibition of protein synthesis. Toxic to both eukaryotic and prokaryotic cells. Believed to act as an acyl-tRNA analogue causing premature chain termination, it has been shown to arrest cells in G2/M phase.

Suppliers

XD BIOCHEMS Ltd

XB7502250

Nantong Xindao Biotech Ltd

NXB13005200

Indofine Chemical Co, Inc.

Bio-340

A.G. Scientific

AS7502250

Santa Cruz Biotechnology, Inc.

108071

Dayang Chem (Hangzhou) Co.,Ltd.

DC15506200

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CSNpharm, Inc.

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Puromycin dihydrochloride hydrate

Chemlyte Solutions

CS17825346

3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride

Iris Biotech GmbH

LS-1053

Prices & Availability

Data is processed

Properties for Puromycin dihydrochloride

Molecular Weight:

544.50 g·mol−1

Melting point:

178-180 °C

Solubility:

Stability Stable. Heat sensitive. Incompatible with strong oxidizing agents. Toxicology Harmful if swallowed. Toxicity data (The meaning of any toxicological abb

Physical Description:

white powder

Safety & Transport Information

Mutation data reported. When heated to decomposition it emits toxic fumes of NOx and HCl.

Risk Codes:

R22 - Harmful if swallowed
R40 - Limited evidence of a carcinogenic effect

Hazard Classes:

6.1(b)

Hazard Symbols:

Storage temperature :

-20°C

RID/ADR certification :

3249

Alternative Distributors of [Puromycin dihydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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