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PTACH

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Formula: C20H26N2O2S2
CAS: 848354-66-5
search Element: ptach

Identification

Structural Formula
PTACH
CAS:
848354-66-5
EINECS:
Molecular Formula:
C20H26N2O2S2
MDL:
SMILES:
CC(C)C(=O)SCCCCCCC(=O)NC1=NC(=CS1)C2=CC=CC=C2
Synonym:
nch 51 ; 2-methylpropanethioicacids-[7-oxo-7-[(4-phenyl-2-thiazolyl)amino]heptyl]ester ; ptach (nch-51) ; cpd 51, s-[6-(4-phenyl-2-thiazolylcarbamoyl)hexyl] thioisobutyrate ; s-(7-oxo-7-((4-phenylthiazol-2-yl)amino)-heptyl) 2-methylpropanethioate


Description

PTACH is a cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor, with an IC50 of 48 nM. PTACH is predicted to exhibit a similar HDAC binding mode as that of SAHA, interacting with the active-site zinc targeting group.


Suppliers

Amadis Chemical Company Limited
ACCL155775
Santa Cruz Biotechnology, Inc.
253326
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CAS equal suppliers

NCH-51;PTACH
Excenen Pharmatech Co., Ltd.
EX-A920
S-(7-Oxo-7-((4-phenylthiazol-2-yl)amino)-heptyl) 2-methylpropanethioate
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC100604

Prices & Availability




Data is processed


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Properties for PTACH

Molecular Weight:
390.569 g·mol−1
Solubility:
Soluble in DMSO (26 mg/ml).
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Safety & Transport Information

Risk Codes:
R41 - Risk of serious damage to eyes
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S39 - Wear eye/face protection
Hazard Symbols:
Xi
Hazard symbol Xi
Storage temperature :
2-8°C
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Alternative Distributors of [PTACH]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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