Protein Kinase Inhibitor, DMAP is a puromycin analog that acts as a protein kinase inhibitor. Selectively induces premature mitosis in mammalian cells. Inhibits TNF-α upregulation of ICAM-1, lipolysis, and the activation of JNK/SAPK. Inhibits p34cdc2/cyclin B (IC50 = 300 µM). Induces apoptosis in S-phase-arrested HeLa cells (~5 mM).
R25 - Toxic if swallowed R27 - Very toxic in contact with skin R36/37/38 - Irritating to eyes, respiratory system and skin
Safety Codes:
S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T+
Storage temperature :
-20°C
RID/ADR certification :
UN 2811 6.1 / PG 1
x
Alternative Distributors of [Protein Kinase Inhibitor, DMAP]
Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.