Protected meropenem

Protected meropenem

96036-02-1

C₃₂H₃₅N₅O₁₁S

O=C([C@]1([H])[C@@H](C)O)N([C@]1([H])[C@]2C)C(C(OCC3=CC=C(C=C3)[N+]([O-])=O)=O)=C2S[C@]4C[C@@H](C(N(C)C)=O)N(C(OCC5=CC=C(C=C5)[N+]([O-])=O)=O)C4

5) protected meropenem ; meropenem intermediates(e-8,mrpm-pnb) ; p-nitrobenzyl(1r,5s,6s)-2-[(3s,5s)-(5-dimethylaminocarbonyl-1-p-nitrobenzyloxycarbonyl)pyrrolidin-3-carboxylate ; 4-nitrobenzyl (5s,6s)-3-[((3s,5s)-5-[(dimethylamino)carbonyl]-1-{[(4-nitrobenzyl)oxy]carbonyl}pyrrolidinyl)sulfanyl]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate ; 3-[[5-[(dimethylamino)carbonypyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4-nitrophenyl)methyl ester ; protected meropenem ; 3-[[5-[(dimethylamino)carbony pyrrolidinyl] thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4-nitrophenyl)methyl ester ; p-nitrobenzyl(4r,5s,6s)-3-[(3s,5s)-(5-dimethylaminocarbonyl-1-p-nitrobenzyloxycarbonyl)-pyrrolidin-3-ylsulfanyl]-6-((r)-1-hydroxy-ethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2ene-4-carboxylate ; 3-[[5-[(dimethylamino)carbonyl-pyrrolidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, (4-nitrophenyl)methyl ester