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Procaine hydrochloride

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Formula: C13H20N2O2.HCl
CAS: 51-05-8

Identification

Structural Formula
Procaine hydrochloride
CAS:
51-05-8
EINECS:
200-077-2
Molecular Formula:
C13H20N2O2.HCl
MDL:
MFCD00013000
SMILES:
CCN(CC)CCOC(=O)C1=CC=C(C=C1)N.Cl
Synonym:
anadolor ; irocaine ; eugerase ; ethocaine ; naucaine ; anestil ; syncaine ; cetain ; paracain ; topokain


Description

Procaine hydrochloride is a salt of the compound Procaine. Procaine is a noted sodium channel blocker with a variety of inhibitory effects. In skeletal muscle, Procaine has been reported to inhibit calcium-induced calcium release (CICR). Procaine is also noted to act as a DNA methylation inhibitor and to cause demethylation and reactivation of methylation-silenced genes such as RARβ and GSTP1. WIF-1 is noted to be reactivated in a cancer cell line and to downregulate the Wnt canonical pathway. In studies utilizing a neuroblastoma cell line (SHEP), Procaine is reported to induce neuronal apoptosis in a manner correlated with lipid solubility of the compound. In an adult mouse muscle cell line (HEK293), the presence of procaine is reported to potently inhibit nicotinic acetylcholine receptors. Procaine is available alone and in its salt form as Procaine HCl.


Suppliers

Anhui Royal Chemical Co., Ltd.
ARC13205280
Aozeal Certified Standards (AOCS), Inc.
P0024.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI303612144
Shandong Ench Chemical Co.,Ltd
SECC13206600
Shandong Minglang Chemical Co., Ltd
SMC15406160
Autech Industry Co.,Limited
AIC11884752
Krada CPS Industry S.L
KCIS9684840
Chemlyte Solutions
CS7922376
H&Z Industry Co.,Ltd
HIC8803520
Indofine Chemical Co, Inc.
021689
B.M.P. Bulk Medicines & Pharmaceuticals GmbH
BBMP19369680
U-Chemo Scientific (Shanghai) Co.,Ltd.
US16726688
CellMark AB
CA4841452
AXO Industry SA
AIS6602640
Caesar & Loretz GmbH
CL8802640
Xiamen Equation Chemical Co.,Ltd
XECC14087040
Sancai Industry Co.,Ltd.
SIC10564224
Aecochem Corp.
AC6161848
Carbone Scientific Co., Ltd.
CS12323696
AK Scientific, Inc.
AS8362508
Xingrui Industry Co., Limited
XIL12765104
Santa Cruz Biotechnology, Inc.
250776
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Hangzhou J&H Chemical Co., Ltd.
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Sigma-Aldrich International GmbH
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Puyer BioPharma Ltd.
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Hangzhou Lingrui Chemical Co., Ltd.
HLC8403360
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CellMark AB
CA264792
Procaine hydrochloride, 99%
Acros Organics BVBA
AOB10264104
2-Diethylaminoethyl 4-aminobenzoate hydrochloride, 99%
Alfa (A Johnson Matthey Company)
A518415552
Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, monohydrochloride
Angene International Limited
AGN-PC-0S9HAL

Prices & Availability




Data is processed


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Properties for Procaine hydrochloride

Molecular Weight:
272.77 g·mol−1
Melting point:
155-156 °C(lit.)
Boiling point:
195-196 °C 17mm
Flash point:
195-196 °C/17mm
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R43 - May cause sensitisation by skin contact
Safety Codes:
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S37/39 - Wear suitable gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
room temp
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Procaine hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Advance Scientific & Chemical, Inc. | Jinan Great Chemical Co., Ltd. | Xiang Ding Chemical International Co., Ltd | New Dragon Industrial Co., Ltd | Watson International Ltd | Prism International Inc. | Molekula GmbH | Shanghai Eagle Chemical Co., Ltd. | Jiangsu Guotai International Group Co., Ltd. | Abtonsmart Chemicals Co., Ltd. | Zouping Mingxing Chemical Co., Ltd. | King Tang Chemical Group Industry Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Changzhou Sunchem Pharmaceutical Chemical Material Co., Ltd. | Clearsynth Canada INC. | Shanghai Chuangxin Chemicals Co., Ltd. | Discovery Fine Chemicals Limited | Unispec Chemicals Co. | Ruiyuan Group Limited | Haihang Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Hefei Golden Chemical Co., Ltd | Ningbo Hi-Tech Biochemicals Co., Ltd. | Jinan Decheng Medical Technology Co., Ltd. | Shanxi Zishan Natural Technology Co., Ltd. | East Chemical Industry Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Pharmfar Co., Ltd. | Wanko Chemical Co., Ltd.

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