Prazosin hydrochloride | CAS 19237-84-4

Element: hydrochloride prazosin

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C-S » Chemicals » prazosin-hydrochloride-PX68502

Identification

Prazosin hydrochloride

CAS:

19237-84-4

EINECS:

242-903-4

Molecular Formula:

C₁₉H₂₁N₅O₄.HCl

MDL:

MFCD00058177

SMILES:

Cl.COC1=CC2=C(C=C1OC)C(N)=NC(=N2)N1CCN(CC1)C(=O)C1=CC=CO1

Synonym:

peripress ; adverszuten ; sinetens ; pratsiol ; alpress lp ; cp-12299-1 ; adversuten ; deprazolin ; hypovasole ; hypovase

Description

Prazosin hydrochloride is an adrenergic α₁-adrenoceptor, α_2B-AR (α_2B-adrenoceptor) and a potent melatonin MT3 receptor antagonist. A study investigated the putative inhibitory effect of prazosin on changes evoked by a NMDA receptor antagonist, MK-801 within the Syrian hamster hypothalamus. This study reported that prazosin was a potent and selective α₁-adrenoceptor antagonist and was able to suppress MK-801 evoked changes, without affecting basal dopamine release in nucleus accumbens. Additionally, in this study prazosin was reported to block MK-801 evoked locomotor stimulation with little affect on basal locomotor activity. Prazosin hydrochloride is an inhibitor of PDE. Also offered in a free base form: Prazosin.

Suppliers

Chemlyte Solutions

CS7922376

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI303612144

H&Z Industry Co.,Ltd

HIC8803520

BoomKing Industrial Co.,Limited

BIC13645456

Xiamen Equation Chemical Co.,Ltd

XECC14087040

Sancai Industry Co.,Ltd.

SIC10564224

Hangzhou Keying Chem Co., Ltd.

HKC13205280

AK Scientific, Inc.

AS8362508

Xingrui Industry Co., Limited

XIL12765104

Santa Cruz Biotechnology, Inc.

204858

Dayang Chem (Hangzhou) Co.,Ltd.

DC13645456

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Prices & Availability

Data is processed

Properties for Prazosin hydrochloride

Molecular Weight:

419.86 g·mol−1

Melting point:

277 - 280 °C

Boiling point:

638.4° C at 760 mmHg (Predicted)

Solubility:

H₂O: 1 mg/mL, clear, colorless

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R62 - Possible risk of impaired fertility

Safety Codes:

S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36 - Wear suitable protective clothing

Hazard Classes:

6.1(b)

Hazard Symbols:

Storage temperature :

Store at RT

RID/ADR certification :

3249

Alternative Distributors of [Prazosin hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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Mol File:

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MSDS:

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