Pirfenidone | CAS 53179-13-8 | Chemical-Suppliers

Element: pirfenidone

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C-S » Chemicals » pirfenidone-PX78877

Identification

Pirfenidone

CAS:

53179-13-8

EINECS:

Molecular Formula:

C₁₂H₁₁NO

MDL:

MFCD00866047

SMILES:

CC1=CN(C(=O)C=C1)C2=CC=CC=C2

Synonym:

pirfenidone(s-7701,amr-69) ; pirespa ; 5-methyl-1-phenyl-2-pyridone ; s-7701,amr-69 ; s-7701 ; 5-methyl-1-phenylpyridin-2-one ; amr-69 ; torasemidetechpirfenidone ; pirfenidone, >=99% ; pirfenidone

Description

Pirfenidone is a small molecule antifibrotic agent. In pulmonary fibrosis studies, Pirfenidone is shown to block collagen production and mitigate the presentation of bleomycin- and cyclophosphamide-induced fibrosis. This intervention appears in part on the transcriptional level, with Pirfenidone exposure correlating to a significant decrease in levels of procollagen I and III gene-assoicated messenger RNA. The antioxidant radical-scavenging activity additionally demonstrated by Pirfenidone suggests a role in protecting against lipid peroxidation, and may attribute to the antifibrotic property of the compound.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI7593036

Shandong Minglang Chemical Co., Ltd

SMC3851540

H&Z Industry Co.,Ltd

HIC220880

Autech Industry Co.,Limited

AIC2971188

Shandong SanYoung Industry Co., Ltd

SSI3851540

Ambeed, Inc.

A196927

Chemlyte Solutions

CS198594

Anhui Cheer-Our Medical Technology Co.,Ltd.

ACMTC4732838

Aozeal Certified Standards (AOCS), Inc.

P0080.00

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT5612805

Hangzhou Verychem Science & Technology Co., Ltd.

HVST5282640

Xiamen Equation Chemical Co.,Ltd

XECC3521760

Hangzhou Zhongqi Chem Co., Ltd

HZC3301320

Quzhou Rundong Chemical Co., Ltd.

QRC3631452

Aecochem Corp.

AC154462

CSNpharm, Inc.

CSN13806

Hangzhou Keying Chem Co., Ltd.

HKC3301320

Hangzhou Lingrui Chemical Co., Ltd.

HLC3851540

Wanko Chemical Co., Ltd.

WC264792

Finetech Industry Limited

FIL2751100

Carbone Scientific Co., Ltd.

CS308924

Hefei Hirisun Pharmatech Co., Ltd

HR011733

CM Fine Chemicals

CFC187748

AK Scientific, Inc.

AS209627

Simagchem Corporation

SC231693

Xingrui Industry Co., Limited

XIL3191276

BOC Sciences

BS132396

Amadis Chemical Company Limited

ACCL3411705

Leap Chem Co., Ltd

LC198594

Santa Cruz Biotechnology, Inc.

203663

Dayang Chem (Hangzhou) Co.,Ltd.

DC3411364

Get Quick Quote

CAS equal suppliers

PIRFENIDONE - BP

Corey Organics PVT Limited

COPL12486240

5-Methyl-1-Phenyl-2(1H)-Pyridinone

Hangzhou J&H Chemical Co., Ltd.

HJC421616864

5-Methyl-1-phenyl-2(1H)-pyridinone

BLD Pharmatech Ltd

BP24487344

5-Methyl-1-phenylpyridin-2(1H)-one

Hangzhou MolCore BioPharmatech Co.,Ltd.

CS18350

2(1H)-Pyridinone,5-methyl-1-phenyl-

Gihi Chemicals Co., Limited

GCL378015120

2(1H)-pyridinone, 5-methyl-1-phenyl-

Angene International Limited

AGN-PC-04X6JR

Prices & Availability

Data is processed

Properties for Pirfenidone

Molecular Weight:

185.22 g·mol−1

Density:

1.14 g/cm³ (Predicted)

Melting point:

96-97 °C

Boiling point:

338.02° C at 760 (Predicted)

Solubility:

DMSO: ≥10 mg/mL, soluble

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed

Safety Codes:

S36 - Wear suitable protective clothing

Hazard Symbols:

Storage temperature :

Store at RT

Alternative Distributors of [Pirfenidone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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5-Methyl-N-(phenyl-14C6)-2-1H-pyridone [Pirfenidone-14C6]