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Pirenzepine Dihydrochloride

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Formula: C19H21N5O2.2(HCl)
CAS: 29868-97-1
search Element: dihydrochloride pirenzepine
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Identification

Structural Formula
Pirenzepine Dihydrochloride
CAS:
29868-97-1
EINECS:
249-907-5
Molecular Formula:
C19H21N5O2.2(HCl)
MDL:
MFCD00055214
SMILES:
CN1CCN(CC1)CC(=O)N2C3=CC=CC=C3C(=O)NC4=C2N=CC=C4.Cl.Cl
Synonym:
maghen ; duogastral ; leblon ; gastricur ; ls519cl2 ; l-s519 ; ulcosan ; renzepin ; tabe ; gasteril


Description

Pirenzepine Dihydrochloride is an analogue of Pirenzepine. Pirenzepine is a selective antagonist for the mAChR M1 (M1 muscarinic receptor) and is reported to block presynaptic mAChR M1 as well as some reported inverse agonist activity. A study investigating the pharmacological characterization of the muscarinic receptors associated with ACh-induced pulmonary vasodilation in a rabbit model of pulmonary hypertension determined the IC50 to be 2.51x10-7M. Additional research studies have investigated the role of Pirenzepine in the pathophysiology of myopia. Other mAChR M1 antagonists offered include Telenzepine.


Suppliers

Ambeed, Inc.
A119911
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Santa Cruz Biotechnology, Inc.
204197
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Prices & Availability




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Properties for Pirenzepine Dihydrochloride

Molecular Weight:
424.32 g·mol−1
Melting point:
248-250°C
Boiling point:
541.7° C at 760 mmHg (Predicted)
Solubility:
H2O: 50 mg/mL
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Safety & Transport Information

Storage temperature :
-20°C Freezer
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Alternative Distributors of [Pirenzepine Dihydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Tongchuang Pharma (Suzhou) Co. Ltd. | Jinan Great Chemical Co., Ltd. | BOC Sciences | Finetech Industry Limited | Clearsynth Canada INC.

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