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Pimelic Diphenylamide 106

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Formula: C20H25N3O2
CAS: 937039-45-7
search Element: diphenylamide pimelic
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Identification

Structural Formula
Pimelic Diphenylamide 106
CAS:
937039-45-7
EINECS:
Molecular Formula:
C20H25N3O2
MDL:
MFCD17010287
SMILES:
CC1=CC=C(C=C1)NC(=O)CCCCCC(=O)NC2=CC=CC=C2N
Synonym:


Description

Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I HDACs (histone deacetylases). With prolonged preincubation (1-3 hours), pimelic diphenylamide inhibits the class I HDAC1, HDAC2, HDAC3, and HDAC8 (IC50 = 150, 760, 370, and 5,000 nM, respectively) but not the class II HDAC4, HDAC5, and HDAC7 (IC50 > 180 μM).


Suppliers

CSNpharm, Inc.
CSN16486
Santa Cruz Biotechnology, Inc.
364589
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CAS equal suppliers

TC-H 106
Santa Cruz Biotechnology, Inc.
362801
TC-H 106
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TC-H 106;Pimelic Diphenylamide 106
Excenen Pharmatech Co., Ltd.
EX-A916
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Finipharma Ltd
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Prices & Availability




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Properties for Pimelic Diphenylamide 106

Molecular Weight:
339.43 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
258.62 °C (Predicted)
Boiling point:
627.25 °C at 760 mmHg (Predicted)
Solubility:
Soluble in ethanol (~0.3 mg/ml), DMSO (~20 mg/ml), DMF (~20 mg/ml), and 1: 1 DMSO: PBS (pH 7.2) (~0.5 mg/ml).
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Safety & Transport Information

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Alternative Distributors of [Pimelic Diphenylamide 106]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

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MSDS:
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