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Phorbol-12,13-dibutyrate

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Formula: C28H40O8
CAS: 37558-16-0
search Element: dibutyrate phorbol

Identification

Structural Formula
Phorbol-12,13-dibutyrate
CAS:
37558-16-0
EINECS:
Molecular Formula:
C28H40O8
MDL:
MFCD00036783
SMILES:
CCCC(=O)O[C@@]12[C@@H]([C@H]([C@]3([C@H](C1C2(C)C)C=C(C[C@]4(C3C=C(C4=O)C)O)CO)O)C)OC(=O)OCCC
Synonym:


Description

Phorbol-12,13-dibutyrate is a strong irritant for mouse skin, but only moderately active as a tumor promoter. This compound activates protein kinase C. Phorbol-12,13-dibutyrate stimulates the phosphorylation of Na+,K+- ATPase, thereby inhibiting its activity. Promotes the expression of inducible NOS in cultured hepatocytes. Phorbol-12,13-dibutyrate is commonly used in binding studies or in applications requiring high concentrations of phorbol compounds.


Suppliers

Santa Cruz Biotechnology, Inc.
202285
Dayang Chem (Hangzhou) Co.,Ltd.
DC14885952
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CAS equal suppliers

phorbol 12,13-dibutyrate
Indofine Chemical Co, Inc.
Bio-943

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Properties for Phorbol-12,13-dibutyrate

Molecular Weight:
504.61 g·mol−1
Density:
1.27 g/cm3 (Predicted)
Boiling point:
623.45° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (partly), chloroform (10 mg/ml, yielding a clear, colorless to faint yellow solution), DMSO (25 mg/ml), ethanol (20 mg/ml), methanol, acetone, and DMF.
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Alternative Distributors of [Phorbol-12,13-dibutyrate]

Producers or manufacturers change the product range from time to time. The following companies
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BOC Sciences

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