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N-(2-Phenylethyl)indomethacin Amide

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Formula: C27H25ClN2O3
CAS: 261766-32-9

Identification

Structural Formula
N-(2-Phenylethyl)indomethacin Amide
CAS:
261766-32-9
EINECS:
Molecular Formula:
C27H25ClN2O3
MDL:
SMILES:
CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)NCCC4=CC=CC=C4
Synonym:
1H-Indole-3-acetamide, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-N-(2-phenylethyl)-


Description

N-(2-Phenylethyl)indomethacin Amide is an aromatic amide of indomethacin recently reported to be a potent and selective reversible inhibitor of Cox-2. N-(2-Phenylethyl)indomethacin Amide inhibits human recombinant and ovine Cox-2 with IC50 of 60 nM and 125 nM, respectively. N-(2-Phenylethyl)indomethacin Amide is over 400-fold less potent as an inhibitor of Cox-1.


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Santa Cruz Biotechnology, Inc.
218925
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CAS equal suppliers

N-(2-Phenylethyl)-indomethacin amide
Santa Cruz Biotechnology, Inc.
SCB432017280

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Properties for N-(2-Phenylethyl)indomethacin Amide

Molecular Weight:
460.95 g·mol−1
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Alternative Distributors of [N-(2-Phenylethyl)indomethacin Amide]

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