4-Phenylbutyric acid | CAS 1821-12-1

Element: phenylbutyric acid

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C-S » Chemicals » phenylbutyric-acid-PX54809

Identification

4-Phenylbutyric acid

CAS:

1821-12-1

EINECS:

217-341-8

Molecular Formula:

C₁₀H₁₂O₂

MDL:

MFCD00004403

SMILES:

C1=CC=C(C=C1)CCCC(=O)O

Synonym:

phenylbutyric acid ; nsc 295 ; akos bbs-00003749 ; benzenebutyric acid ; timtec-bb sbb008452 ; 4-phenybutytic acid ; 4-benzene acid ; benzenebutanoicacid ; rarechem al bo 0178 ; buphenyl

Description

4-Phenylbutyric acid is a chemical chaperone, which suppresses oxidative stress by attenuating endoplasmic reticulum stress. 4-Phenylbutyric acid increases the expression of type 2 deiodinase (D2), via the accumulation of Dio2 mRNA. Studies indicate that 4-Phenylbutyric acid affects genes such as Ucp-1, Ucp-3 and Pgc-1α in a D2-dependent manner. The activation of these genes is thought to increase T3 production. Diabetic studies conducted on mice suggest that 4-Phenylbutyric acid normalizes serum glucose levels.

Suppliers

Shandong SanYoung Industry Co., Ltd

SSI14005600

Chemlyte Solutions

CS7202160

Autech Industry Co.,Limited

AIC10804320

Zhejiang Jiasi Chemical Co., Ltd.

ZJC13205280

Seqens International SAS

SIS9603840

Richman Chemical Inc.,

RCI8803520

Xiamen Equation Chemical Co.,Ltd

XECC12806400

Merck Schuchardt OHG

MSO8003200

AK Scientific, Inc.

AS7602280

Simagchem Corporation

SC8402520

Xingrui Industry Co., Limited

XIL11604640

Santa Cruz Biotechnology, Inc.

232961

Chemos GmbH & Co. KG

CC8002400

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CAS equal suppliers

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Biesterfeld Spezialchemie GmbH

BS11403420

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CM Fine Chemicals

CFC6462584

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Chemieliva Pharmaceutical Co., Ltd.

CP13303990

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Leap Chem Co., Ltd

LC6842052

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Zhejiang Hongxin Chemical

ZHC9503800

4-Phenybutytic acid

Skyrun Industrial Co., Ltd.

SI10263078

4-Phenybutytic acid

Purestar Chem Enterprise Co., Ltd.

PCE12925168

4-Phenybutytic acid

Hangzhou Lingrui Chemical Co., Ltd.

HLC13305320

Benzenebutanoic acid

Angene International Limited

AGN-PC-006I8K

N-Pentylboronic acid

Molekula

30454452

p-Phenylbutyric acid

Dayang Chem (Hangzhou) Co.,Ltd.

DC12404960

p-Phenylbutyric acid

Gihi Chemicals Co., Limited

GCL10804320

4-Phenylbutanoic acid

Hangzhou J&H Chemical Co., Ltd.

HJC13025208

4-Phenylbutanoic acid

Ambeed, Inc.

A148817

4-Phenylbutanoic acid

Key Organics Limited

PS-4322

4-Phenylbutanoic acid

CSNpharm, Inc.

CSN23643

4-Phenylbutanoic acid

BLD Pharmatech Ltd

BP7562268

Prices & Availability

Data is processed

Properties for 4-Phenylbutyric acid

Molecular Weight:

164.2 g·mol−1

Melting point:

49-51 °C(lit.)

Boiling point:

165 °C10 mm Hg(lit.)

Flash point:

>230 ºF

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing

Hazard Symbols:

Alternative Distributors of [4-Phenylbutyric acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

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MSDS:

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