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Phenylbutazone

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Formula: C19H20N2O2
CAS: 50-33-9
search Element: phenylbutazone

Identification

Structural Formula
Phenylbutazone
CAS:
50-33-9
EINECS:
200-029-0
Molecular Formula:
C19H20N2O2
MDL:
MFCD00005500
SMILES:
CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3
Synonym:
a 7514 ; reudo ; azolid ; azdid ; butoz ; bute ; buzon ; uzone ; pbz ; kadol


Description

Phenylbutazone is a compound of research interest as an anti-inflammatory and anti-proliferative agent. Several studies have investigated Phenylbutazone as an anti-inflammatory agent and its role in mediating prostaglandin synthesis. Phenylbutazone may be of interest regarding research into anti-proliferative effects as well, especially in colorectal cancer studies. In studies with human colon cancer cell lines investigating anti-proliferative capabilities of NSAIDs, Phenylbutazone was noted to have intermediate anti-proliferative potency as compared to other NSAIDs. Phenylbutazone is an inhibitor of Cox (cyclooxygenase) that is also a substrate for peroxidation by Cox.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI9663864
Shandong Minglang Chemical Co., Ltd
SMC4901960
H&Z Industry Co.,Ltd
HIC2801120
Krada CPS Industry S.L
KCIS3081540
Chemlyte Solutions
CS252756
Ambeed, Inc.
A208133
Tianjin Norland Biotech Co., Ltd.
TNB4621848
AXO Industry SA
AIS210840
Xiamen Equation Chemical Co.,Ltd
XECC4482240
Sancai Industry Co.,Ltd.
SIC3361344
Aecochem Corp.
AC196588
CSNpharm, Inc.
CSN17306
Sigma-Aldrich International GmbH
SI4481344
Carbone Scientific Co., Ltd.
CS3921176
Hefei Hirisun Pharmatech Co., Ltd
HR130844
CM Fine Chemicals
CFC238952
AK Scientific, Inc.
AS266798
Xingrui Industry Co., Limited
XIL4061624
Leap Chem Co., Ltd
LC252756
Santa Cruz Biotechnology, Inc.
204843
Dayang Chem (Hangzhou) Co.,Ltd.
DC4341736
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CAS equal suppliers

Phenylbutazone, Pharma
Salsbury Chemicals, Inc.
SC10563168
4-Butyl-1,2-diphenylpyrazolidine-3,5-dione
Salsbury Chemicals, Inc.
SC30249072
4-Butyl-1,2-diphenylpyrazolidine-3,5-dione
BLD Pharmatech Ltd
BP22686804
3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-
Angene International Limited
AGN-PC-07A25I

Prices & Availability




Data is processed


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Properties for Phenylbutazone

Molecular Weight:
308.37 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
104-107 °C
Boiling point:
~424.9° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (1 mg/ml at 25° C), ethanol (62 mg/ml at 25° C), methanol, DMSO (62 mg/ml at 25° C), and DMF (25 mg/ml).
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Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36 - Irritating to eyes
R36/37/38 - Irritating to eyes, respiratory system and skin
R42/43 - May cause sensitization by inhalation and skin contact
R45 - May cause cancer
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Classes:
6.1(b)
Hazard Symbols:
Xn, T, F
Hazard symbol T Hazard symbol F Hazard symbol Xn
Storage temperature :
-20 °C Freezer
RID/ADR certification :
3249
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Alternative Distributors of [Phenylbutazone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | Spectrum Chemical Mfg. Corp. | BOC Sciences | ABCR GmbH & Co. KG | Junwee Chemical Co., Ltd. | Jinan Great Chemical Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Xiang Ding Chemical International Co., Ltd | New Dragon Industrial Co., Ltd | Watson International Ltd | 3B Scientific Corporation | Wintersun Chemical | TCI Europe NV | Shanghai Eagle Chemical Co., Ltd. | Lianyungang JF International Trade Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | Changzhou Sinly Pharmchem Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Clearsynth Canada INC. | Chengdu Qiaofeng Technological Development Co., Ltd. | Haihang Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Jinjiangchem Corporation | ShangHai Biochempartner Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Wanko Chemical Co., Ltd.

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