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Phalloidin

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Formula: C35H48N8O11S
CAS: 17466-45-4
search Element: phalloidin
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Identification

Structural Formula
Phalloidin
CAS:
17466-45-4
EINECS:
241-484-5
Molecular Formula:
C35H48N8O11S
MDL:
MFCD03427567
SMILES:
CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C)C(C)O
Synonym:
phalloidin, amanita phalloides ; cyclic(l-alanyl-d-threonyl-l-cysteinyl-cis-4-hydroxy-l-prolyl-l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl), cyclic (3.fwdarw.6)-sulfide ; cyclo(l-ala-d-thr-l-cys(1)-l-c4hyp-l-ala-l-trp2(1)-4,5'-dihydroxy-l-leu-) ; phalloidin ; nsc523214 ; phalloidin from amanita phalloides ; phalloidine ; pto-l-tryptophyl-4,5-dihydroxy-l-leucyl),cyclic(3,6)-sulfide ; cyclic(l-alanyl-d-threonyl-l-cysteinyl-cis-4-hydroxy-l-prolyl-l-alanyl-2-merca


Description

Phalloidin is a heptapeptide phallotoxin produced by Amanita phalloides, the death cap mushroom. Phalloidin binds and stabilizes filamentous F-actin, preventing the dissociation of paired filaments and disturbing the natural equilibrium between filamentous (polymeric) and globular (monomeric) actin in the cell. Actin is used by the cell for mechanical processes such as growth, scaffolding of the cytoskeleton, and locomotion, and disruption of this actin equilibrium destroys cellular functioning.


Suppliers

Indofine Chemical Co, Inc.
Bio-934
Santa Cruz Biotechnology, Inc.
202763
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Prices & Availability




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Properties for Phalloidin

Molecular Weight:
788.87 g·mol−1
Melting point:
280-282° C(.6H2O)
Solubility:
Soluble in methanol, ethanol (10 mg/ml), water (1 mg/ml, warm), and DMF.
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Safety & Transport Information

Risk Codes:
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
Safety Codes:
S22 - Do not breathe dust
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+
Hazard symbol T+
RID/ADR certification :
UN 3462 6.1 / PG 2
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Alternative Distributors of [Phalloidin]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
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MSDS:
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