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Phallacidin

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Formula: C37H50 N8 O13 S
CAS: 26645-35-2
search Element: phallacidin

Identification

Structural Formula
Phallacidin
CAS:
26645-35-2
EINECS:
Molecular Formula:
C37H50 N8 O13 S
MDL:
MFCD00063359
SMILES:
CC1C(=O)NC2CC3=C(NC4=CC=CC=C34)SCC(C(=O)N5CC(CC5C(=O)N1)O)NC(=O)C(NC(=O)C(NC(=O)C(NC2=O)CC(C)(CO)O)C(C)C)C(C(=O)O)O
Synonym:
cyclic(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro ; phallacidin(7ci,8ci,9ci) ; phallacidin from amanita phalloides ; 6)-sulfide ; cyclo[ala-2-mercapto-trp-4,5-dihydroxy-leu-val-erythro-3-hydroxy-d-asp-cys-cis-4-hydroxy-pro] ; phallacidine ; cyclo(l-alanyl-2-mercapto-l-tryptophyl-4,5-dihydroxy-l-leucyl-l-valyl-erythro-3-hydroxy-d-a-aspartyl-l-cysteinyl-cis-4-hydroxy-l-prolyl),cyclic (2® ; phallacidin ; phallicidin ; -3-hydroxy-d-alpha-aspartyl-l-cysteinyl-cis-4-hydroxy-l-prolyl)cyclic(2-6)-s ; 18,9-(iminoethaniminoethaniminoethaniminomethano)-17h-pyrrolo[1',2':5,6][1,5,8,11]thiatriazacyclopentadecino[15,14-b]indole,cyclic peptide deriv. ; cyclo[l-ala-l-trp2(1)-4,5-dihydroxy-l-leu-l-val-[(3s)-3-hydroxy-d-asp-]-l-cys(1)-l-c4hyp-]


Description

Phallacidin is a member of the phallotoxin family of mushroom toxins isolated from Amanita phalloides with biological activity similar to Phalloidin, which binds and stabilizes filamentous F-actin, preventing the dissociation of paired filaments and disturbing the natural equilibrium between filamentous (polymeric) and globular (monomeric) actin in the cell. Actin is used by the cell for mechanical processes such as growth, scaffolding of the cytoskeleton, and locomotion, and disruption of this actin equilibrium destroys cellular functioning. This product has a carboxy group that Phalloidin does not, making it useful for coupling reactions to fluorescent molecules.


Suppliers

Indofine Chemical Co, Inc.
Bio-320
Santa Cruz Biotechnology, Inc.
204840
Dayang Chem (Hangzhou) Co.,Ltd.
DC3411364
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Properties for Phallacidin

Molecular Weight:
847.01 g·mol−1
Density:
1.54 g/cm3
Boiling point:
1435.2 °C
Flash point:
821.8 °C
Solubility:
Soluble in water, DMSO, DMF, and methanol.
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Safety & Transport Information

A poison by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx and SOx.
Risk Codes:
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
Safety Codes:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+
Hazard symbol T+
RID/ADR certification :
1544
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Alternative Distributors of [Phallacidin]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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Downloads

Mol File:
-/-
MSDS:
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