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Perphenazine

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Formula: C21H26ClN3OS
CAS: 58-39-9
search Element: perphenazine

Identification

Structural Formula
Perphenazine
CAS:
58-39-9
EINECS:
200-381-5
Molecular Formula:
C21H26ClN3OS
MDL:
SMILES:
C1CN(CCN1CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)Cl)CCO
Synonym:
sch3940 ; perphenan ; 1-piperazineethanol,4-[3-(2-chloro-10h-phenothiazin-10-yl)propyl]- ; triphenot ; f-mon ; chlorperphenazine ; decentan ; etaperazine ; trifaron ; 1-piperazineethanol,4-[3-(2-chlorophenothiazin-10-yl)propyl]- (8ci) ; chloriprozine ; perfenazine ; 4-(3-(2-chlorophenothiazin-10-yl)propyl)-1-piperazineethanol ; 2-chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine ; 2-chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl] propyl phenothiazine ; mutabom ; fentazine duolets ; trilifan ; trilafon ; pzc ; perfenil ; g-[4-(b-hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine ; etaperazin ; sch 3940 ; fentazin syrup ; ethaperazine ; 1-(2-hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine ; fentazin ; tranquisan ; emesinal ; nsc 150866 ; perphenazin ; thilatazin


Description

Perphenazine is a D2DR inhibitor which inhibits the glutamate dehydrogenase in vitro. Perphenazine also acts as a α-adrenergic receptor antagonist and σ-receptor agonist. Studies indicate that uncharged Perphenazine is better at forming complexes with cyclodextrins. In addition, Perphenazine forms more stable complexes with cyclodextrins than fluphenazine. Studies show that Perphenazine enhances the expression of CD71 on K562 cells, while at the same time inhibiting the proliferation of these cells.


Suppliers

Aozeal Certified Standards (AOCS), Inc.
P0005.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8283312
Shandong SanYoung Industry Co., Ltd
SSI4201680
Chemlyte Solutions
CS216648
Xiamen Equation Chemical Co.,Ltd
XECC3841920
CSNpharm, Inc.
CSN11685
Hangzhou Lingrui Chemical Co., Ltd.
HLC4201680
Sigma-Aldrich International GmbH
SI3841152
Carbone Scientific Co., Ltd.
CS3361008
AK Scientific, Inc.
AS228684
Santa Cruz Biotechnology, Inc.
208161
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
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CAS equal suppliers

2-(4-(3-(2-Chloro-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol
Leap Chem Co., Ltd
LC1260037800
2-(4-(3-(2-Chloro-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethanol
Wanko Chemical Co., Ltd.
WC1680050400

Prices & Availability




Data is processed


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Properties for Perphenazine

Molecular Weight:
403.97 g·mol−1
Density:
1.253 g/cm3
Melting point:
95-98 °C C
Boiling point:
580.4 °C at 760 mmHg
Flash point:
304.8 °C
Solubility:
Soluble in Chloroform and Methanol
Physical Description:
off-white to pale yellow solid
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
R43 - May cause sensitisation by skin contact
Safety Codes:
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8°C
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Alternative Distributors of [Perphenazine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Jiangsu Guotai International Group Co., Ltd. | Hangzhou Think Chemical Co., Ltd. | Hwasun Pharmaceutical Co.Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Changzhou An-Yuan Imp. & Exp. Corporation | Shanghai Boyle Chemical Co., Ltd. | BOC Sciences | Xiamen Hisunny Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Clearsynth Canada INC.

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