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Pelitinib

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Formula: C24H23ClFN5O2
CAS: 257933-82-7
search Element: pelitinib
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Identification

Structural Formula
Pelitinib
CAS:
257933-82-7
EINECS:
Molecular Formula:
C24H23ClFN5O2
MDL:
MFCD09837868
SMILES:
CCOC1=C(NC(=O)C=CCN(C)C)C=C2C(=C1)N=CC(C#N)=C2NC1=CC(Cl)=C(F)C=C1
Synonym:
(2e)-n-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide ; pelitinib, >=98% ; (e)-n-(4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide ; n-[4-(3-chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)-2(e)-but·namide ; ekb-569 pelitinib ; pelitinib(ekb-569) ; (2e)-n-[4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide ; pelitinib ; way-ekb 569 ; 2-butenamide, n-[4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-, (2e)-


Description

Pelitinib is a tyrosine kinase inhibitor that covalently binds to EGFR, inhibiting receptor phosphorylation and thus inhibiting signal transduction from EGFR. This induces apoptosis and thus leads to suppression of growth in tumor cell lines.


Suppliers

Aea.ltd
A63126
+
Chemlyte Solutions
CS162486
+
CSNpharm, Inc.
CSN11666
Pharmacore Co., Limited
PL207621
AK Scientific, Inc.
AS171513
+
Capot Chemical Co., Ltd.
25889
+
Leap Chem Co., Ltd
LC162486
+
Santa Cruz Biotechnology, Inc.
208155
Get Quick Quote

CAS equal suppliers

EKB569
Aea.ltd
A4284
(E)-N-(4-(3-Chloro-4-fluorophenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide
Hangzhou MolCore BioPharmatech Co.,Ltd.
MC110755

Prices & Availability




Data is processed


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Properties for Pelitinib

Molecular Weight:
467.93 g·mol−1
Density:
1.34
Melting point:
173-178 °C
Boiling point:
~655.5° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (13 mg/ml at 25° C), methanol, water (<1 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).
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Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
Safety Codes:
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
-20 °C Freezer
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Alternative Distributors of [Pelitinib]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Evershine Chemical Co.,Ltd. | Rongkang Industry Co.,Ltd - (NSTU Chemicals Hanggzhou Co.,) | Jinan Great Chemical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Shanghai Boyle Chemical Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | U-Chemo Holding Co., Limited | Apichem Chemical Technology Co., Ltd. | Wuhan Sunrise Technology Development Company Ltd. | Rosewell Industry Co., Ltd. | Suchem Pharma Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Watson International Ltd | BOC Sciences | Shanghai Arbor Chemical Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Clearsynth Canada INC.

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