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Oxymetazoline Hydrochloride

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Formula: C16H24 N2 O . Cl H
CAS: 2315-02-8

Identification

Structural Formula
Oxymetazoline Hydrochloride
CAS:
2315-02-8
EINECS:
219-015-0
Molecular Formula:
C16H24 N2 O . Cl H
MDL:
MFCD00058147
SMILES:
CC1=CC(=C(C(=C1CC2=NCCN2)C)O)C(C)(C)C.Cl
Synonym:
phenol, 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-,monohydrochloride (8ci) ; neo-synephrine 12 hour ntz ; nafrinehydrochloride ; phenol,3-[(4,5-dihydro-1h-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-,hydrochloride (1:1) ; phenol,6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethyl-, hydrochloride (7ci) ; neonabel ; 2,6-dimethyl-4-tertiarybutyl-3-hydroxyphenyl)methylimidazolinehydrochloride ; nasivin ; 2-(4-tert-butyl-2,6-dimethyl-3-hydroxybenzyl)-2-imidazoliniumchloride ; afrazine ; oxrmetazoline ; oxymetazoline hcl ; oxilin ; afrinhydrochloride ; nostrilla ; respir ; ocuclear ; akos 92115 ; iliadin ; h 990 ; dristan long-lastingnasal mist ; duration 12 hour nasal spray ; iliadinhydrochloride ; 6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimethylphenol hydrochloride ; 4-way nasal spray ; oxymetazolinechloride ; afrin ; neo-synephrine 12 hour ; phenol,3-[(4,5-dihydro-1h-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-,monohydrochloride (9ci) ; oxymetazoline hydrochloride ; allerest 12 hour nasal spray ; afrin hydrochloride ; nafrine ; 4-way nasal 12 hour spray ; duration ; oxymetazoline chloride ; sch 9384


Description

Oxymetazoline Hydrochloride is a direct sympathomimetic agent. Is a nonselective adrenomimetic of α1A-AR and α2A-AR (α1-AR and α2-AR adrenergic receptor) agonists. Since vascular beds widely express α1 receptors, the action of Oxymetazoline results in vasoconstriction due to its action on endothelial α2 receptors. Oxymetazoline Hydrochloride is an inhibitor of SR-2C and an activator of SR-1A, SR-1B, SR-1D and SR-2C.


Suppliers

Chemlyte Solutions
CS9722916
AXO Industry SA
AIS8103240
Xiamen Equation Chemical Co.,Ltd
XECC17288640
Sancai Industry Co.,Ltd.
SIC12965184
Aecochem Corp.
AC7562268
Sigma-Aldrich International GmbH
SI17285184
Carbone Scientific Co., Ltd.
CS15124536
AK Scientific, Inc.
AS10263078
Xingrui Industry Co., Limited
XIL15666264
Leap Chem Co., Ltd
LC9722916
Santa Cruz Biotechnology, Inc.
203172
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N-(2-Aminoethyl)-2-[4-(1,1-dimethylethyl)-3-hydroxy-2,6-dimethylphenyl] acetamide HCl
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Properties for Oxymetazoline Hydrochloride

Molecular Weight:
296.88 g·mol−1
Density:
1.08 g/cm3
Melting point:
300-303° C (dec.)
Boiling point:
431.9°C at 760 mmHg
Flash point:
215°C
Solubility:
H2O: soluble
Transport Information:
UN 2811
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Safety & Transport Information

Poison by ingestion, subcutaneous, intraperitoneal, and intravenous routes. Experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NOx and HCl. An adrenergic agent.
Risk Codes:
Safety Codes:
S22 - Do not breathe dust
S28 - After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer)
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+
Hazard symbol T+
Storage temperature :
Store at RT
RID/ADR certification :
UN 2811 6.1 / PG 1
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Alternative Distributors of [Oxymetazoline Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Shanghai Eagle Chemical Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Jinan Great Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | Nebula Chemicals Co, Ltd.

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