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Oxymatrine

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Formula: C15H24N2O2
CAS: 16837-52-8
search Element: oxymatrine

Identification

Structural Formula
Oxymatrine
CAS:
16837-52-8
EINECS:
Molecular Formula:
C15H24N2O2
MDL:
MFCD00210339
SMILES:
C1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]
Synonym:
pachycarpidine ; matrine n-oxide ; ammothamnine ; oxymatrine(p) ; oxymatrine,(s) ; matrine,1-oxide ; oxymatrine ; matrine oxide ; kurainone ; oxymatrine std.


Description

Oxymatrine is a compound from Sophora japonica, which has many biologically functions such as the inhibition of IL-6 and IL-1β mRNA expression. Studies indicate that Oxymatrine functions as an inhibitor of hepatitis B virus (HBV) by downregulating the gene coding for heat-stress cognate 70 (Hsc70), which is required for HBV DNA replication. In addition, Oxymatrine inhibits Toll-like receptor 4 (TLR-4)/nuclear factor kappa-B (NF-κB) and reduce apoptosis in neurons. Furthermore, Oxymatrine acts as an inhibitor of β-catenin in MCF-7 breast cancer cells via suppressing its expression.


Suppliers

Chengdu Pufeide Biotech. Co., Ltd
CPB3301320
H&Z Industry Co.,Ltd
HIC200800
Indofine Chemical Co, Inc.
06-024
Sancai Industry Co.,Ltd.
SIC240960
Hainan Zhongxin Chemical Co., Ltd.
HZC3401360
CSNpharm, Inc.
CSN19333
Pharmacore Co., Limited
PL230690
BOC Sciences
BS120360
Santa Cruz Biotechnology, Inc.
279937
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Xiamen Equation Chemical Co.,Ltd
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Fox Chemicals GmbH
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Radix Flavescentis Extract
H&Z Industry Co.,Ltd
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Prices & Availability




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Properties for Oxymatrine

Molecular Weight:
264.36 g·mol−1
Melting point:
197.6-198 °C
Boiling point:
572.82 °C (Predicted)
Solubility:
Soluble in water (53 mg/ml at 25 °C), ethanol (53 mg/ml at 25 °C), methanol (10 mg/ml), DMSO (53 mg/ml at 25 °C), and DMF (~10 mg/ml).
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Safety & Transport Information

Risk Codes:
R22 - Harmful if swallowed
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
2-8 °C
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Alternative Distributors of [Oxymatrine]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

CCS. CHEM. Co., Ltd. | 3B Scientific Corporation | Shanghai Eagle Chemical Co., Ltd. | Northchem (Tianjin) International Trading Co., Ltd. | Xingcheng Chempharm Co., Ltd. | Shanghai Tauto Biotech Co., Ltd. | ChengDu KaiXin Technology Development Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai Brightol International Co., Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Pharmfar Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Greenlife Biotechnology Co.,Ltd. | Chengdu Conut Intl. Co., Ltd. | BOC Sciences | BioBioPha Co., Ltd. | All Right Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Clearsynth Canada INC.

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