S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) | CAS 38048-32-7

Element: nitrobenzyl thioinosine nbmpr nbti

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C-S » Chemicals » nitrobenzyl-thioinosine-nbti-nbmpr-PX77070

Identification

S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR)

CAS:

38048-32-7

EINECS:

253-753-4

Molecular Formula:

C₁₇H₁₇N₅O₆S

MDL:

MFCD00005745

SMILES:

C1=CC(=CC=C1CSC2=NC=NC3=C2N=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)[N+](=O)[O-]

Synonym:

nbti ; 6-[(4-nitrobenzyl)sulfanyl]-9-(β-d-ribofuranosyl)-9h-purine ; inosine,6-s-[(4-nitrophenyl)methyl]-6-thio- ; s-(p-nitrobenzyl)-6-thioinosine ; 6-[(4-nitrobenzyl)thio]-9-b-d-ribofuranosylpurine ; nbmpr ; 4-nitrobenzyl-6-mercaptoinosine ; 9h-purine, 6-[[(4-nitrophenyl)methyl]thio]-9-β-d-ribofuranosyl- ; nsc 296962 ; s-(4-nitrobenzyl)-6-thioinosine ; s-(4-nitrobenzyl)-6-thioinosine,99% ; nitrobenzylthioinosine ; s-(p-nitrobenzyl)-6-mercapto-9-b-d-ribofuranosylpurine ; 4-nitrobenzylthioinosine ; 6-(p-nitrobenzylthio)inosine

Description

S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR) is a small molecule inhibitor of equilibrative nucleoside transporter (ENT) proteins. These transport proteins are described in relation to their sensitivity to NBMPR, designated as either es (NBMPR-sensitive) or ei (NBMPR-insensitive). They provide good research tools anticancer, antiviral, cardioprotective, and neuroprotective agents. Inhibition of ENT1 by NBMPR blocks the uptake and transport of adenosine, which affects the regulation of extracellular adenosine levels and the cardiac system signaling associated with adenosine.

Suppliers

Santa Cruz Biotechnology, Inc.

200117

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CAS equal suppliers

S-(4-Nitrobenzyl)-6-thioinosine

Hangzhou J&H Chemical Co., Ltd.

HJC384415376

S-(4-Nitrobenzyl)-6-thioinosine

Santa Cruz Biotechnology, Inc.

SCB372014880

S-(4-Nitrobenzyl)-6-thioinosine

Amadis Chemical Company Limited

ACCL384419220

Prices & Availability

Data is processed

Properties for S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR)

Molecular Weight:

419.41 g·mol−1

Density:

1.78 g/cm3

Melting point:

187-190 °C(lit.)

Boiling point:

770.2 °C at 760 mmHg

Flash point:

419.6 °C

Solubility:

0.1 M HCl: slightly soluble

Safety & Transport Information

Safety Codes:

S24/25 - Avoid contact with skin and eyes

Storage temperature :

2-8°C

Alternative Distributors of [S-(4-Nitrobenzyl)-6-thioinosine (NBTI, NBMPR)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Acros Organics BVBA | 3B Scientific Corporation | BOC Sciences

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