Nimodipine-d7 | CAS 1246815-36-0

Element: nimodipine

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C-S » Chemicals » nimodipine-PX80271

Identification

Nimodipine-d7

CAS:

1246815-36-0

EINECS:

Molecular Formula:

C₂₁H₁₉D₇N₂O₇

MDL:

SMILES:

C(C1=C(C(C(=C(N1[H])C([H])([H])[H])C(=O)OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])[2H])(C2=C(C(=C(C(=C2[H])[H])[H])[N+](=O)[O-])[H])[H])C(=O)OC(C(OC([H])([H])[H])([H])[H])([H])[H])([H])([H])[H]

Synonym:

Description

Nimodipine-d7 is a deuterium-labeled analogue of Nimodipine. Nimodipine is a L-type Ca²⁺ channel within the dihydropyridine drug class. Nimodipine has several reported effects, specifically within vascular and neuronal test systems. In anesthetized cats, intravenous administration of Nimodipine is reported to cause pial arterial vasodilation. In rats, a study on the effect of Nimodipine on convulsions produced via various methods noted that the threshold of pentylenetetrazol convulsion induction was raised after Nimodipine administration. Nimodipine has also been reported to be selective for cerebral vasculature and may be useful for migraine research studies. Chronic Nimopidine treatment in aged rats has been reported to prevent age-induced learning deficits and may be associated with a slight increase of synaptosomal Ca²⁺ binding proteins from the cerebral cortex.

Suppliers

Santa Cruz Biotechnology, Inc.

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Properties for Nimodipine-d7

Molecular Weight:

425.48 g·mol−1

Melting point:

116-121°C (lit.)

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Alternative Distributors of [Nimodipine-d7]

Producers or manufacturers change the product range from time to time. The following companies
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Clearsynth Canada INC.