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Nifuroxazide

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Formula: C12H9N3O5
CAS: 965-52-6
search Element: nifuroxazide

Identification

Structural Formula
Nifuroxazide
CAS:
965-52-6
EINECS:
213-522-0
Molecular Formula:
C12H9N3O5
MDL:
MFCD00079482
SMILES:
C1=CC(=CC=C1C(=O)N/N=C/C2=CC=C(O2)[N+](=O)[O-])O
Synonym:
adral ; ercefurol ; r.c.27-109 ; diarlidan ; 27-109rc ; bacifurane ; pentofuryl ; ercefuryl ; dicoferin ; rc 30-109


Description

Nifuroxazide is a nitrofuran compound inhibitor of STAT transcription factor signaling. Nifuroxazide is described to block constitutive phosphorylation of STAT3 by reducing Jak kinase autophosphorylation, decreasing the viability of myeloma cells depending on constitutive STAT3 activity for survival while not affecting normal peripheral blood mononuclear cells. Nifuroxazide produces decreases in tyrosine phosphorylation of Jak2 and Tyk2, and showed no effects on EGF receptor tyrosine kinase or Src kinase, indicating a relative specificity of Nifuroxazide for Jak2 and Tyk2. Nifuroxazide shows no inhibition of Akt or MAPK phosphorylation.


Suppliers

Lori Industry Co., Ltd
LI264792
H&Z Industry Co.,Ltd
HIC240960
Autech Industry Co.,Limited
AIC3241296
Shandong SanYoung Industry Co., Ltd
SSI4201680
Create Chemical Co., Ltd.
CC300900
Chemlyte Solutions
CS216648
Aozeal Certified Standards (AOCS), Inc.
N0005.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8283312
AXO Industry SA
AIS180720
X´ian Taicheng Chem Co., Ltd
XTC3481392
BoomKing Industrial Co.,Limited
BIC3721488
Xiamen Equation Chemical Co.,Ltd
XECC3841920
Hainan Zhongxin Chemical Co., Ltd.
HZC4081632
Aecochem Corp.
AC168504
CSNpharm, Inc.
CSN11557
Sigma-Aldrich International GmbH
SI3841152
Finetech Industry Limited
FIL3001200
Carbone Scientific Co., Ltd.
CS3361008
AK Scientific, Inc.
AS228684
Simagchem Corporation
SC252756
Xingrui Industry Co., Limited
XIL3481392
BOC Sciences
BS144432
Leap Chem Co., Ltd
LC216648
Santa Cruz Biotechnology, Inc.
204128
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
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Prices & Availability




Data is processed


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Properties for Nifuroxazide

Molecular Weight:
275.22 g·mol−1
Density:
~1.5 g/cm3 (Predicted)
Melting point:
281-283 °C
Boiling point:
477.25° C (Predicted)
Solubility:
Soluble in water (practically insoluble), chloroform (practically insoluble), ethyl ether (0.01g/>100ml) (practically insoluble), Methanol (0.01g/100ml) (very slightly soluble), 1 N Sodium hydroxide (1.0g/30ml), and DMSO.
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Safety & Transport Information

Storage temperature :
Refrigerator, Under Inert Atmosphere
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Alternative Distributors of [Nifuroxazide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences | Jinan Great Chemical Co., Ltd. | Anix-Chem Limited | Xiang Ding Chemical International Co., Ltd | Watson International Ltd | 3B Scientific Corporation | Taizhou Creating Chemical Co., Ltd. | Jinan Haohua Industry Co., Ltd. | Nantong Chem-Tech. (Group) Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Shanghai AOKChem Group Limited | Ningbo Samreal Chemical Co., Ltd. | Changzhou Elly Chemical Company | Xiamen Hisunny Chemical Co., Ltd. | Jinjiangchem Corporation | East Chemical Industry Co., Ltd. | API Vanguard | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Wanko Chemical Co., Ltd. | Angel Synthesis Co., Ltd

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