Neurokinin-1 Receptor Antagonist | CAS 337505-63-2

Element: antagonist neurokinin receptor

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C-S » Chemicals » neurokinin-receptor-antagonist-PX70797

Identification

Neurokinin-1 Receptor Antagonist

CAS:

337505-63-2

EINECS:

Molecular Formula:

C₂₁H₁₆ClN₅OS

MDL:

SMILES:

C1=CC=C(C=C1)N2C(=NN=C2SCC(=O)NC3=CC(=CC=C3)Cl)C4=CC=NC=C4

Synonym:

Acetamide, N-(3-chlorophenyl)-2-[[4-phenyl-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-

Description

Neurokinin-1 Receptor Antagonist is a triazolyl-amide compound that acts as a high-affinity (K_i = 251 nM) antagonist for NK1, the substance P-specific neurokinin receptor. Shown to compete with substance P binding to NK1 on whole CHO cells. Exhibits similar pharmacophore features as, but is structurally distinct from, CP-96345.

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Santa Cruz Biotechnology, Inc.

222057

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Properties for Neurokinin-1 Receptor Antagonist

Molecular Weight:

421.9 g·mol−1

Solubility:

Soluble in DMSO

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Alternative Distributors of [Neurokinin-1 Receptor Antagonist]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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Mol File:

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MSDS:

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