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Neostigmine Bromide

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Formula: C12H19BrN2O2
CAS: 114-80-7
search Element: neostigmine bromide

Identification

Structural Formula
Neostigmine Bromide
CAS:
114-80-7
EINECS:
204-054-8
Molecular Formula:
C12H19BrN2O2
MDL:
MFCD00011795
SMILES:
CN(C)C(=O)OC1=CC=CC(=C1)[N+](C)(C)C.[Br-]
Synonym:
stigmanolbromide ; neoesserin ; stigmosanbromide ; eustigminbromide ; neostigmin ; neoserinebromide ; prostigmin ; prostigmine ; juvastigmin ; prostigmi


Description

Neostigmine bromide is a reversible acetylcholine esterase inhibitor that binds to the anionic binding site of AChE. This allows acetylcholine to remain within the synapse and stimulate AChR. It is used in the treatment of myasthenia gravis and to reverse the effects of muscle relaxants.


Suppliers

Ambeed, Inc.
A198984
Aozeal Certified Standards (AOCS), Inc.
N0030.00
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI262210488
H&Z Industry Co.,Ltd
HIC7603040
Caesar & Loretz GmbH
CL7602280
Xiamen Equation Chemical Co.,Ltd
XECC12166080
Sancai Industry Co.,Ltd.
SIC9123648
CSNpharm, Inc.
CSN11539
Hangzhou Lingrui Chemical Co., Ltd.
HLC13305320
Sigma-Aldrich International GmbH
SI12163648
AK Scientific, Inc.
AS7222166
Simagchem Corporation
SC7982394
Xingrui Industry Co., Limited
XIL11024408
Leap Chem Co., Ltd
LC6842052
Santa Cruz Biotechnology, Inc.
204816
Dayang Chem (Hangzhou) Co.,Ltd.
DC11784712
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Properties for Neostigmine Bromide

Molecular Weight:
303.2 g·mol−1
Melting point:
175-177 °C(lit.)
Solubility:
H2O: 1 g/mL
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R25 - Toxic if swallowed
R26/27/28 - Very toxic by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R42/43 - May cause sensitization by inhalation and skin contact
Safety Codes:
S22 - Do not breathe dust
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S37/39 - Wear suitable gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
Hazard Classes:
6.1(a)
Hazard Symbols:
T+, T
Hazard symbol T Hazard symbol T+
Storage temperature :
-20°C Freezer
RID/ADR certification :
UN 2811 6.1 / PG 2
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Alternative Distributors of [Neostigmine Bromide]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Spectrum Chemical Mfg. Corp. | Inter-Chemical Ltd. | Hallochem Pharma Co., Ltd. | ABCR GmbH & Co. KG | Nantong Chem-Tech. (Group) Co., Ltd. | TCI Europe NV | Pharmasi Chemicals Co., Ltd. | Hangzhou Sida Organic Chemical Co., Ltd. | Hangzhou Yanshan Chemical Co., Ltd. | Share Chemical Co., Ltd. | Atomole Scientific Co., Ltd. | Anix-Chem Limited | Hangzhou Pharma & Chem Co. Ltd. | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Watson International Ltd | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Gihi Chemicals Co., Limited

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