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(-)-Nebivolol

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Formula: C22H25 F2 N O4
CAS: 118457-16-2
search Element: nebivolol

Identification

Structural Formula
(-)-Nebivolol
CAS:
118457-16-2
EINECS:
Molecular Formula:
C22H25 F2 N O4
MDL:
SMILES:
C1CC2=C(C=CC(=C2)F)O[C@@H]1[C@H](CNC[C@@H]([C@@H]3CCC4=C(O3)C=CC(=C4)F)O)O
Synonym:
nebivolol impurity a (l-nebivolol) ; r-67145 ; (-)-nebivolol ; 2h-1-benzopyran-2-methanol,a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-, (as,a's,2r,2's)- ; [2s-[2r*[r*[r*(s*)]]]]-α,α'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro- 2h-1-benzopyran-2-methanol ; (as,a,2r,2)-a,a[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2h-1-benzopyran-2-methanol] ; [2r,2's,αs,α's,(-)]-α,α'-[iminobis(methylene)]bis(6-fluoro-3,4-dihydro-2h-1-benzopyran-2-methanol) ; (2r)-2-[(s)-1-hydroxy-2-[[(s)-2-hydroxy-2-[[(2s)-3,4-dihydro-6-fluoro-2h-1-benzopyran]-2-yl]ethyl]amino]ethyl]-6-fluoro-3,4-dihydro-2h-1-benzopyran ; (as,a's,2r,2's)-a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2h-1-benzopyran-2-methanol] ; 2h-1-benzopyran-2-methanol,a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-,[2s-[2r*[r*[r*(s*)]]]]- ; levonebivolol ; (αs,α's,2r,2's)-α,α'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2h-1-benzopyran-2-methanol] ; l-nebivolol ; r 67145


Description

(-)-Nebivolol is a β1-Adrenergic blocker. The compound is commonly used as an antihypertensive.


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L-Nebivolo
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Nebivolol impurity A
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Nebivolol EP Impurity A (L-Nebivolol)
Aozeal Certified Standards (AOCS), Inc.
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Properties for (-)-Nebivolol

Molecular Weight:
405.44 g·mol−1
Density:
1.309 g/cm3
Melting point:
135-137 °C
Boiling point:
600.5°C at 760 mmHg
Flash point:
316.9°C
Solubility:
Chloroform and Methanol