C-6 NBD-dihydro-Ceramide | CAS 114301-95-0

Element: ceramide dihydro

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C-S » Chemicals » nbd-dihydro-ceramide-PX65048

Identification

C-6 NBD-dihydro-Ceramide

CAS:

114301-95-0

EINECS:

Molecular Formula:

C₃₀H₅₁N₅O₆

MDL:

SMILES:

CCCCCCCCCCCCCCCC(C(CO)NC(=O)CCCCCNC1=CC=C(C2=NON=C12)[N+](=O)[O-])O

Synonym:

c6-nbd-dihydroceramide ; n-hexanoyl-nbd-l-threo-dihydrosphingosine ; n-hexanoyl-nbd-d-erythro-dihydrosphingosine ; n-c6-nbd-l-threo-dihydrosphingosine, fluorescent ; n-c6-nbd-d-erythro-dihydrosphingosine, fluorescent

Description

C-6 NBD ceramide is a biologically active fluorescent analog of short chain, membrane-permeable ceramides. It is as effective as C-6 ceramide in the inhibition of viral glycoprotein transport through the Golgi.1 C-6 NBD ceramide has been used as a fluorescent substrate for the activity of UDP-glucose:ceramide glucosyltransferase2 and to demonstrate the translocation of glucocerebroside and sphingomyelin from the Golgi to the plasma membrane.3 C-6 NBD-dihydro-Ceramide is structurally indistinguishable to C-6 NBD ceramide, except it contains a saturated bond in the C-4/C-5 position of the sphingosine backbone.