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Nafamostat mesylate

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Formula: C19H17N5O2.2(CH4O3S)
CAS: 82956-11-4
search Element: nafamostat mesylate

Identification

Structural Formula
Nafamostat mesylate
CAS:
82956-11-4
EINECS:
Molecular Formula:
C19H17N5O2.2(CH4O3S)
MDL:
MFCD00941430
SMILES:
CS(=O)(=O)O.CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC3=C(C=C2)C=C(C=C3)C(=N)N)N=C(N)N
Synonym:
futhan ; nafamostat mesilate, nafamostat mesylate ; nafamostat mesylate(fut-175) ; fut-175 ; nafamstatmesilate ; nafamostat mesylate, >=98% ; nafomastatmesilate ; ester,dimethanesulfonate ; nafamostat mesylate ; nafamstat mesylate


Description

Nafamostat mesylate is a highly effective tryptase (Ki=95.3 pM) inhibitor. The compound has the ability to promote synthesis of interferon-γ, tumor necrosis factor-α, IL-12, and IL-18. Additionally, Nafamostat mesylate can induce production of intercellular adhesion molecules-1, B7.1, B7.2, CD40 and CD40 ligand in human blood mononuclear cells. Nafamostat mesylate is an anticoagulant and has been shown to decrease levels of plasma myeloperoxidase, and has also been used in ERCP pancreatitis studies. Nafamostat mesylate is an inhibitor of Factor X, Factor XII, granzyme A and KLK.


Suppliers

Shandong SanYoung Industry Co., Ltd
SSI13305320
Create Chemical Co., Ltd.
CC9502850
Chemlyte Solutions
CS6842052
Ambeed, Inc.
A570309
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI262210488
Lori Industry Co., Ltd
LI8362508
Xiamen Equation Chemical Co.,Ltd
XECC12166080
Reafon Industry Co., Ltd.
RI9502850
Reafon Industry Co., Ltd.
RF-RL003
Aecochem Corp.
AC5321596
Fox Chemicals GmbH
FC6842052
CSNpharm, Inc.
CSN11508
Carbone Scientific Co., Ltd.
CS10643192
Pharmacore Co., Limited
PL8742622
Hefei Hirisun Pharmatech Co., Ltd
HR130370
AK Scientific, Inc.
AS7222166
Simagchem Corporation
SC7982394
Xingrui Industry Co., Limited
XIL11024408
Capot Chemical Co., Ltd.
30346
Zehao Industry Co., Ltd.
ZI9122736
BOC Sciences
BS4561368
Amadis Chemical Company Limited
ACCL11785890
Leap Chem Co., Ltd
LC6842052
Santa Cruz Biotechnology, Inc.
201307
Dayang Chem (Hangzhou) Co.,Ltd.
DC11784712
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CAS equal suppliers

Nafamostat mesilate
Sancai Industry Co.,Ltd.
SIC9123648
6-Amidino-2-naphthyl 4-guanidino-benzoate dimethanesulfonate
Salsbury Chemicals, Inc.
SC576017280
6-Carbamimidoylnaphthalen-2-yl 4-guanidinobenzoate dimethanesulfonate
BLD Pharmatech Ltd
BP496814904

Prices & Availability




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Properties for Nafamostat mesylate

Molecular Weight:
539.58 g·mol−1
Melting point:
259-261 °C
Solubility:
Soluble in DMSO (>10 mg/ml), water (25 mg/ml) Note: Phosphate-containing buffers may cause precipitation, and ethanol (<1 mg/mL) at 25° C.
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Safety & Transport Information

Storage temperature :
Room temp
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Alternative Distributors of [Nafamostat mesylate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Shaanxi Dasheng Pharmaceutical Tech Co., Ltd. | New Dragon Industrial Co., Ltd | Sanowart Group Co., Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Rovathin Pharmatech Co., Ltd | Jinan Great Chemical Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | All Right Chemical Co., Ltd. | Watson International Ltd | BOC Sciences | Wolves R&D Chemicals | Sciyu Biotech Co., Ltd. | Finetech Industry Limited | Jinan Haohua Industry Co., Ltd. | Skyrun Industrial Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Green Fine Chemical (Shanghai) Co., Ltd. | Gihi Chemicals Co., Limited | Amadis Chemical Co., Ltd.

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