Mycophenolic acid | CAS 24280-93-1

Element: mycophenolic acid

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C-S » Chemicals » mycophenolic-acid-PX73450

Identification

Mycophenolic acid

CAS:

24280-93-1

EINECS:

246-119-3

Molecular Formula:

C₁₇H₂₀O₆

MDL:

MFCD00036814

SMILES:

CC1=C(C(=C(C2=C1COC2=O)O)C/C=C(C)/CCC(=O)O)OC

Synonym:

Description

Mycophenolic Acid is an immunosuppressant small molecule isolated as a fermentation product from several Penicillium species. Mycophenolic Acid functions as a potent reversible inhibitor of IMPDH (inosine monophosphate dehydrogenase), leading to a depletion of GMP in the cell and interruption of the de novo synthesis of purines necessary for lymphocyte proliferation. This powerful immunosuppressant property has been exploited in studies on organ transplant survival, rhuematoid arthritis, and psoriasis. Derivitization of Mycophenolic Acid to the morpholinoethyl ester, known as Mycophenolate mofetil, presents a greater bioavailability for the active compound.

Suppliers

Shandong SanYoung Industry Co., Ltd

SSI11904760

Chemlyte Solutions

CS6121836

Autech Industry Co.,Limited

AIC9183672

Aozeal Certified Standards (AOCS), Inc.

M0007.08

Ambeed, Inc.

A399663

H&Z Industry Co.,Ltd

HIC6802720

Indofine Chemical Co, Inc.

Bio-292

A.G. Scientific

AS5101530

Serva Electrophoresis GmbH

SE8842652

Biesterfeld Spezialchemie GmbH

BS10203060

X´ian Taicheng Chem Co., Ltd

XTC9863944

Xiamen Equation Chemical Co.,Ltd

XECC10885440

Quzhou Rundong Chemical Co., Ltd.

QRC11224488

Daming Changda Co., Ltd.

DC8162448

Aecochem Corp.

AC4761428

CSNpharm, Inc.

CSN19396

Sigma-Aldrich International GmbH

SI10883264

scienTEST - bioKEMIX GmbH

S-B8503400

Iris Biotech GmbH

LS-1042

CM Fine Chemicals

CFC5782312

AK Scientific, Inc.

AS6461938

Xingrui Industry Co., Limited

XIL9863944

Leap Chem Co., Ltd

LC6121836

Santa Cruz Biotechnology, Inc.

200110

Dayang Chem (Hangzhou) Co.,Ltd.

DC10544216

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CAS equal suppliers

Mycophenolic acid, 98%

Alfa (A Johnson Matthey Company)

A14084224

6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-Methyl-4-hexenoic acid

Hangzhou J&H Chemical Co., Ltd.

HJC2356094240

6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid

Key Organics Limited

DS-1638

(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid

Manchester Organics Limited

H47250

(E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoic acid

Pharmacore Co., Limited

PL2900387009

(4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid

BLD Pharmatech Ltd

BP2469674088

Prices & Availability

Data is processed

Properties for Mycophenolic acid

Molecular Weight:

320.3 g·mol−1

Density:

1.29 g/cm³ (Predicted)

Melting point:

141-145 °C

Boiling point:

611.61 °C at 760 mmHg (Predicted)

Solubility:

Soluble in ethanol, methanol (50 mg/ml), chloroform, dichloromethane, 0.1 N NaOH (10 mg/ml), ether, DMSO (50 mg/ml), benzene (sparingly soluble), and toluene (sparingly soluble). Insoluble in water.

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Alternative Distributors of [Mycophenolic acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified