Moxifloxacin Hydrochloride | CAS 186826-86-8

Element: hydrochloride moxifloxacin

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C-S » Chemicals » moxifloxacin-hydrochloride-PX72185

Identification

Moxifloxacin Hydrochloride

CAS:

186826-86-8

EINECS:

Molecular Formula:

C₂₁H₂₄FN₃O₄.HCl

MDL:

MFCD00949117

SMILES:

COC1=C2C(=CC(=C1N3C[C@@H]4CCCN[C@@H]4C3)F)C(=O)C(=CN2C5CC5)C(=O)O.Cl

Synonym:

proflox ; bay-12-8039 ; avelox ; actira ; moxiflaxacin hcl ; moxifloxacinehcl ; avalox ; bay12-8039 hcl ; moxifloxacinehydrochloride ; moxifloxacin hcl

Description

Moxifloxacin Hydrochloride is the hydrochloride salt preparation of Moxifloxacin, an 8-methoxy-fluoroquinone compound with broad-spectrum bactericidal activity against gram-positive and gram-negative strains. 8-methoxy-fluoroquinones are described to inhibit the activities of Topo II (DNA gyrase) and topoisomerase IV. The 8-methoxy group of Moxifloxacin is suggested to confer a lowered propensity for resistance development as compared to other C-8 substituted quinolones, and Moxifloxacin demonstrates potent activity against wild-type and first-step gyrase- and topoisomerase IV-resistant mutants. Moxifloxacin shows activity against methicillin-susceptible staphylococci, penicillin-susceptible and penicillin-resistant pneumococci, penicillin-susceptible and penicillin-resistant viridans group streptococci, group A streptococci, M. catarrhalis, and H. influenzae in vitro.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI358814352

H&Z Industry Co.,Ltd

HIC10404160

Wuhan PharmChem Co., LTD.

WP13003900

Shandong SanYoung Industry Co., Ltd

SSI18207280

Nantong Xindao Biotech Ltd

NXB13525408

Ambeed, Inc.

A250011

Chemlyte Solutions

CS9362808

Aozeal Certified Standards (AOCS), Inc.

M0006.01

Guangzhou Topwork Chemical Co., Ltd.

GTC18727488

Xiamen Equation Chemical Co.,Ltd

XECC16648320

Aecochem Corp.

AC7282184

Hangzhou Keying Chem Co., Ltd.

HKC15606240

Finetech Industry Limited

FIL13005200

Carbone Scientific Co., Ltd.

CS14564368

AK Scientific, Inc.

AS9882964

BOC Sciences

BS6241872

Amadis Chemical Company Limited

ACCL16128060

Santa Cruz Biotechnology, Inc.

205758

Dayang Chem (Hangzhou) Co.,Ltd.

DC16126448

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BLD Pharmatech Ltd

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Prices & Availability

Data is processed

Properties for Moxifloxacin Hydrochloride

Molecular Weight:

437.89 g·mol−1

Melting point:

323.9-325° C

Boiling point:

636.4° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (24 mg/ml), DMSO (88 mg/ml at 25° C), and ethanol (<1 mg/ml at 25° C).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Hazard Classes:

irritant

Storage temperature :

2-8 °C

Alternative Distributors of [Moxifloxacin Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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Mol File:

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MSDS:

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Moxifloxacin Hydrochloride Impurity D (EP)

Moxifloxacin hydrochloride, 97%