Mifepristone | CAS 84371-65-3 | Chemical-Suppliers

Element: mifepristone

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C-S » Chemicals » mifepristone-PX70431

Identification

Mifepristone

CAS:

84371-65-3

EINECS:

Molecular Formula:

C₂₉H₃₅NO₂

MDL:

MFCD00867226

SMILES:

CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O

Synonym:

mifegyne ; ru486 ; mifeprex ; mifepriston ; mifestone ; r38486 ; ru-38486 ; vgx 410 ; c-1073 ; ru486-6

Description

Mifepristone is a progesterone (PR) and glucocorticoid receptor (GR) antagonist which has demonstrated the ability to suppress activation of NFκB, a nuclear transcription factor that affects the expression of various adhesion molecules and several inflammatory genes. It is also an inhibitor of the progesterone receptor. Mifepristone has been found to decrease basal bcl-2 messenger RNA levels in CA1 neural regions and the dentate gyrus. Experiments have shown that mifepristone potentially exhibits an inhibitory effect on embryo implantation via regulation of FAS and FAS-L apoptosis gene expression. Additionally, mifepristone displays anti-angiogenic characteristics via suppression of vascular endothelial growth factor (VEGF) production. Mifepristone may also prevent intracellular peroxide accumulation and cell death induced by hydrogen peroxide, glutamate, β-amyloid protein, or neurotoxins that have been associated with certain neurodegenerative disorders.

Suppliers

H&Z Industry Co.,Ltd

HIC240960

Aea.ltd

A84168

Chemlyte Solutions

CS216648

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI8283312

Crystal Pharma (Gadea Grupo Farmacéutico)

CP5042016

X´ian Taicheng Chem Co., Ltd

XTC3481392

Hainan Zhongxin Chemical Co., Ltd.

HZC4081632

Aecochem Corp.

AC168504

CSNpharm, Inc.

CSN11444

Hangzhou Keying Chem Co., Ltd.

HKC3601440

Hangzhou Lingrui Chemical Co., Ltd.

HLC4201680

Wanko Chemical Co., Ltd.

WC288864

Finetech Industry Limited

FIL3001200

Carbone Scientific Co., Ltd.

CS3361008

CM Fine Chemicals

CFC204816

AK Scientific, Inc.

AS228684

Xingrui Industry Co., Limited

XIL3481392

Leap Chem Co., Ltd

LC216648

Santa Cruz Biotechnology, Inc.

203134

Dayang Chem (Hangzhou) Co.,Ltd.

DC3721488

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CAS equal suppliers

Mifepristone d6

Salsbury Chemicals, Inc.

SC7202160

Prices & Availability

Data is processed

Properties for Mifepristone

Molecular Weight:

429.59 g·mol−1

Density:

1.19 g/cm³ (Predicted)

Melting point:

195-198 °C

Boiling point:

628.61° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (partly), DMF (~30 mg/ml), ethanol (50 mg/ml), methanol, and DMSO (86 mg/ml at 25° C).

Safety & Transport Information

Risk Codes:

R60 - May impair fertility
R61 - May cause harm to the unborn child

Safety Codes:

S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

Storage temperature :

2-8°C

Alternative Distributors of [Mifepristone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified