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Mifepristone

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Formula: C29H35NO2
CAS: 84371-65-3
search Element: mifepristone

Identification

Structural Formula
Mifepristone
CAS:
84371-65-3
EINECS:
Molecular Formula:
C29H35NO2
MDL:
MFCD00867226
SMILES:
CC#C[C@@]1(CC[C@@H]2[C@@]1(C[C@@H](C3=C4CCC(=O)C=C4CC[C@@H]23)C5=CC=C(C=C5)N(C)C)C)O
Synonym:
mifegyne ; ru486 ; mifeprex ; mifepriston ; mifestone ; r38486 ; ru-38486 ; vgx 410 ; c-1073 ; ru486-6


Description

Mifepristone is a progesterone (PR) and glucocorticoid receptor (GR) antagonist which has demonstrated the ability to suppress activation of NFκB, a nuclear transcription factor that affects the expression of various adhesion molecules and several inflammatory genes. It is also an inhibitor of the progesterone receptor. Mifepristone has been found to decrease basal bcl-2 messenger RNA levels in CA1 neural regions and the dentate gyrus. Experiments have shown that mifepristone potentially exhibits an inhibitory effect on embryo implantation via regulation of FAS and FAS-L apoptosis gene expression. Additionally, mifepristone displays anti-angiogenic characteristics via suppression of vascular endothelial growth factor (VEGF) production. Mifepristone may also prevent intracellular peroxide accumulation and cell death induced by hydrogen peroxide, glutamate, β-amyloid protein, or neurotoxins that have been associated with certain neurodegenerative disorders.


Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8283312
H&Z Industry Co.,Ltd
HIC240960
Aea.ltd
A84168
Chemlyte Solutions
CS216648
Crystal Pharma (Gadea Grupo Farmacéutico)
CP5042016
X´ian Taicheng Chem Co., Ltd
XTC3481392
Hainan Zhongxin Chemical Co., Ltd.
HZC4081632
Aecochem Corp.
AC168504
CSNpharm, Inc.
CSN11444
Hangzhou Keying Chem Co., Ltd.
HKC3601440
Hangzhou Lingrui Chemical Co., Ltd.
HLC4201680
Wanko Chemical Co., Ltd.
WC288864
Finetech Industry Limited
FIL3001200
Carbone Scientific Co., Ltd.
CS3361008
CM Fine Chemicals
CFC204816
AK Scientific, Inc.
AS228684
Xingrui Industry Co., Limited
XIL3481392
Leap Chem Co., Ltd
LC216648
Santa Cruz Biotechnology, Inc.
203134
Dayang Chem (Hangzhou) Co.,Ltd.
DC3721488
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CAS equal suppliers

Mifepristone d6
Salsbury Chemicals, Inc.
SC7202160

Prices & Availability




Data is processed


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Properties for Mifepristone

Molecular Weight:
429.59 g·mol−1
Density:
1.19 g/cm3 (Predicted)
Melting point:
195-198 °C
Boiling point:
628.61° C at 760 mmHg (Predicted)
Solubility:
Soluble in water (partly), DMF (~30 mg/ml), ethanol (50 mg/ml), methanol, and DMSO (86 mg/ml at 25° C).
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Safety & Transport Information

Risk Codes:
R60 - May impair fertility
R61 - May cause harm to the unborn child
Safety Codes:
S22 - Do not breathe dust
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Symbols:
T
Hazard symbol T
Storage temperature :
2-8°C
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Alternative Distributors of [Mifepristone]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Inter-Chemical Ltd. | Hunan Steroid Chemicals Co., Ltd | Beijing Keyifeng (KYF) Biorech Develop. Co., Ltd. | Kinfon Pharmaceutical and Chemical Service Co., Ltd. | Zhejiang Xianju Greeleaf Pharmaceutical Factory | Xiangfan Goto Chemical Co., Ltd. | Ningbo Zhengrun Chemicals Co., Ltd. Exp. Dept. | CCS. CHEM. Co., Ltd. | Argosi International Co., Ltd. | 3B Scientific Corporation | Beijing Zizhu Pharmaceutical Co., Ltd. | Zhejiang Xianju Pharmaceutical Co., Ltd. | Taizhou Baida Pharma Co., Ltd. | Nanjing King-Pharm Co., Ltd. | Hubei Gedian Humanwell Pharmaceutical Co., Ltd. | Pharmasi Chemicals Co., Ltd. | TCI Europe NV | Zhejiang Materials Industry Chemical Group Co., Ltd. | New Dragon Industrial Co., Ltd | Orichem International Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Shanghai Brightol International Co., Ltd. | Hangzhou Pharma & Chem Co. Ltd. | Lanospharma Laboratories Co., Ltd. | Jinan Great Chemical Co., Ltd. | Tai Hua Industries Co., Limited | ZhangJiaGang CAE International Trading Co., Ltd. | Jinjiangchem Corporation | Benro Internatinal Co., Linc | Hangzhou Holypharm Biotech Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | API Vanguard | All Right Chemical Co., Ltd. | Watson International Ltd | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Yongyi Chemicals Group Co., Ltd. | BOC Sciences | Jinan Haohua Industry Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Shaanxi TOP Pharm Chemical Co.,Ltd. | Trademax Phamaceuticals & Chemicals Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Clearsynth Canada INC. | Haihang Industry Co., Ltd.

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