mGluR5 Ligand, CDPPB | CAS 781652-57-1

Element: ligand mglur5 cdppb

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C-S » Chemicals » mglur-ligand-cdppb-PX76376

Identification

mGluR5 Ligand, CDPPB

CAS:

781652-57-1

EINECS:

Molecular Formula:

C₂₃H₁₆N₄O

MDL:

MFCD12828752

SMILES:

C1=CC=C(C=C1)C2=NN(C(=C2)NC(=O)C3=CC=CC(=C3)C#N)C4=CC=CC=C4

Synonym:

Description

mGluR5 Ligand, CDPPB is a pyrazole amide compound that crosses the blood-brain barrier and acts as a potent, selective, reversible, positive allosteric modulator for metabotropic mGluR-5 (glutamate receptor subtype 5). This also exerts anti-psychotic-like effects. It is reported to potentiate the response to glutamate (~300 nM) in CHO-mGluR-5 cells (EC₅₀ = 10 nM. It does not potentiate the activity of other glutamate receptors.

Suppliers

Amadis Chemical Company Limited

ACCL18609300

Santa Cruz Biotechnology, Inc.

221942

Dayang Chem (Hangzhou) Co.,Ltd.

DC18607440

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CAS equal suppliers

3-Cyano-N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamide

Hangzhou MolCore BioPharmatech Co.,Ltd.

MC111376

Prices & Availability

Data is processed

Properties for mGluR5 Ligand, CDPPB

Molecular Weight:

364.4 g·mol−1

Density:

1.20 g/cm³ (Predicted)

Melting point:

264.38° C (Predicted)

Boiling point:

523.28° C at 760 mmHg (Predicted)

Solubility:

Soluble in DMSO (10 mg/mL).

Safety & Transport Information

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Alternative Distributors of [mGluR5 Ligand, CDPPB]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

Mol File:

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MSDS:

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