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Metronidazole

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Formula: C6H9N3O3
CAS: 443-48-1
search Element: metronidazole
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Identification

Structural Formula
Metronidazole
CAS:
443-48-1
EINECS:
207-136-1
Molecular Formula:
C6H9N3O3
MDL:
MFCD00009750
SMILES:
CC1=NC=C(N1CCO)[N+](=O)[O-]
Synonym:
flagil ; cont ; nida ; elyzol ; bexon ; eumin ; klion ; clont ; nalox ; klont


Description

Metronidazole is a limited spectrum antibiotic that actively deters the growth of protozoa, anaerobic gram-positive, and anaerobic gram-negative bacteria. The first use of this antibiotic was to suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.


Suppliers

XD BIOCHEMS Ltd
XB195585
+
Krada CPS Industry S.L
KCIS2861430
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI8973588
+
Wuhan PharmChem Co., LTD.
WP325975
+
Shandong Ench Chemical Co.,Ltd
SECC3901950
+
Nantong Xindao Biotech Ltd
NXB3381352
+
Create Chemical Co., Ltd.
CC325975
+
Shandong Minglang Chemical Co., Ltd
SMC4551820
+
Chemlyte Solutions
CS234702
+
Lori Industry Co., Ltd
LI286858
+
Refine Chemical Co.,Ltd.
RCC3121248
+
Shandong Lanhai Industry Co.,Ltd.
SLIC4292145
+
Autech Industry Co.,Limited
AIC3511404
+
H&Z Industry Co.,Ltd
HIC2601040
+
Aozeal Certified Standards (AOCS), Inc.
M0013.00
+
Ambeed, Inc.
A114755
+
Indofine Chemical Co, Inc.
Bio-266
Pharma Greven GmbH
PG234702
Tessenderlo Chemie
TC234702
Hangzhou Cherry Pharmaceutical Technology Co., Ltd.
HCPT6633315
+
B.M.P. Bulk Medicines & Pharmaceuticals GmbH
BBMP5722860
+
AXO Industry SA
AIS195780
+
X´ian Taicheng Chem Co., Ltd
XTC3771508
+
Xiamen Equation Chemical Co.,Ltd
XECC4162080
+
Sancai Industry Co.,Ltd.
SIC3121248
+
Arakato Development Ltd
AD299897
+
Hainan Zhongxin Chemical Co., Ltd.
HZC4421768
+
Aecochem Corp.
AC182546
+
CSNpharm, Inc.
CSN11432
Hangzhou Keying Chem Co., Ltd.
HKC3901560
+
Sigma-Aldrich International GmbH
SI4161248
+
scienTEST - bioKEMIX GmbH
S-B3251300
+
Finetech Industry Limited
FIL3251300
+
Xingrui Industry Co., Limited
XIL3771508
+
Zehao Industry Co., Ltd.
ZI312936
+
BOC Sciences
BS156468
+
Leap Chem Co., Ltd
LC234702
+
Santa Cruz Biotechnology, Inc.
204805
Dayang Chem (Hangzhou) Co.,Ltd.
DC4031612
+
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Prices & Availability




Data is processed


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Properties for Metronidazole

Molecular Weight:
171.15 g·mol−1
Density:
~0.5 g/cm3 (Predicted)
Melting point:
159-161 °C(lit.)
Boiling point:
~405.4° C at 760 mmHg (Predicted)
Solubility:
acetic acid: 0.1 M, clear, faintly yellow
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Hazard Statements

GHS07

GHS03
Harmful
  • Acute toxicity (oral, dermal, inhalation), category 4
  • Skin irritation, categories 2, 3
  • Eye irritation, category 2A
  • Skin sensitization, category 1
  • Specific target organ toxicity following single exposure, category 3
    - Respiratory tract irritation
    - Narcotic effects
    • Not used
  • with the "skull and crossbones" pictogram
  • for skin or eye irritation if:
  • the "corrosion" pictogram also appears
  • the "health hazard" pictogram is used to indicate respiratory sensitization
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R40 - Limited evidence of a carcinogenic effect
R45 - May cause cancer
R46 - May cause inheritable genetic damage
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
S7 - Keep container tightly closed
Hazard Symbols:
Xn, T, F
Hazard symbol T Hazard symbol F Hazard symbol Xn
Storage temperature :
2-8°C
x

Alternative Distributors of [Metronidazole]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Cfm Oskar Tropitzsch GmbH | Spectrum Chemical Mfg. Corp. | BOC Sciences | Inter-Chemical Ltd. | Hefei Photochem Trading Co., Ltd | Jinan Great Chemical Co., Ltd. | Gihi Chemicals Co., Limited | Xiamen Topusing Chemical Co., Ltd. | New Dragon Industrial Co., Ltd | Nantong Bestime Chemical Co., Ltd. | 3B Scientific Corporation | Goldenchem Co., Ltd. | Asian Trade Link | Shanxi Jinjin Chemical Co., Ltd. | Molekula GmbH | Hallochem Pharma Co., Ltd. | Hubei Tianmeng Chemical Co., Ltd. | Yongyi Chemicals Group Co., Ltd. | Jiangsu Guotai International Group Co., Ltd. | Hwasun Pharmaceutical Co.Ltd. | scienTEST | Pharmasi Chemicals Co., Ltd. | Luotian Hengxingyuan Chemical Co., Ltd. | King Tang Chemical Group Industry Co., Ltd. | Shanghai Chemicals & Pharmaceuticals Co., Limited | Jinan Haohua Industry Co., Ltd. | Ningbo Pangs Chem Int'l Co., Ltd. | China Yangzhou Wandong Medical Co., Ltd. | Changzhou An-Yuan Imp. & Exp. Corporation | Clearsynth Canada INC. | Suzhou Rovathin Pharmatech Co., Ltd | Discovery Fine Chemicals Limited | Zibo Panxin Pharmaceutical Co., Ltd. | Long Island Pharmaceutical & Chemical Co. Ltd. | Chengdu Qiaofeng Technological Development Co., Ltd. | Suzhou Vosun Chemical Co.,Ltd. | Dandong Qianjin Trade Co., Ltd. | Haihang Industry Co., Ltd. | Xiamen Hisunny Chemical Co., Ltd. | Ningbo Hi-Tech Biochemicals Co., Ltd. | Jinjiangchem Corporation | Suzhou Sibian Chemical Technology Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Hubei Yuancheng Saichuang Tech.Co.,Ltd | Wanko Chemical Co., Ltd. | Mei Le Shi Limited | Angel Synthesis Co., Ltd

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