Methylene blue trihydrate | CAS 7220-79-3

Element: trihydrate methylene blue

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C-S » Chemicals » methylene-blue-trihydrate-PX66131

Identification

Methylene blue trihydrate

CAS:

7220-79-3

EINECS:

Molecular Formula:

C₁₆H₁₈ClN₃S.3(H₂O)

MDL:

MFCD00150008

SMILES:

CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]

Synonym:

methylene blue hydrate ; methylene blue, cp ; methylene blue trihy ; methylene blue ts ; ci no 52015 ; methylene blue bb ; methylenebluepract ; ci 52015 ; basic blue 9 hydrate ; c.i. 52015 trihydrate

Description

Methylene Blue acts as a GCS (guanylyl cyclase) inhibitor, biological stain and redox indicator. Methylene Blue inhibits tau filament formation. Additionally, Methylene Blue is also reported to inhibit NOS_s (nitric oxide synthase). Methylene Blue is widely used to inhibit cGMP-mediated processes. Methylene Blue has been observed to dose-dependently induce cytotoxicity in U-373 MG human astrocytoma and SK-N-MC human neuroblastoma cells. Furthermore Methylene Blue is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes, and thus exhibit antimuscarinic effects on IK, ACh and ICa. Methylene Blue has also been reported to inhibit endothelium-dependent relaxation of isolated blood vessels.

Suppliers

H&Z Industry Co.,Ltd

HIC15006000

Shanghai Worldyang Chemical Co., Ltd.

SWC277511100

Aecochem Corp.

AC10503150

Hangzhou Lingrui Chemical Co., Ltd.

HLC262510500

Wanko Chemical Co., Ltd.

WC18005400

Finetech Industry Limited

FIL18757500

Xingrui Industry Co., Limited

XIL21758700

Leap Chem Co., Ltd

LC13504050

Santa Cruz Biotechnology, Inc.

203744

Dayang Chem (Hangzhou) Co.,Ltd.

DC23259300

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Prices & Availability

Data is processed

Properties for Methylene blue trihydrate

Molecular Weight:

373.9 g·mol−1

Density:

0.98 g/mL at 25 °C

Melting point:

190 °C (dec.)(lit.)

Flash point:

14 °C

Solubility:

Soluble in water (50 mg/ml), ethanol (70 mg/ml), alcohol, and chloroform. Insoluble in ether.

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R22 - Harmful if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S24/25 - Avoid contact with skin and eyes
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S7 - Keep container tightly closed

Hazard Symbols:

Xn, F

Storage temperature :

Store at RT.

RID/ADR certification :

UN 1170 3 / PG 2

Alternative Distributors of [Methylene blue trihydrate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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