Methoxsalen (8-Methoxypsoralen) | CAS 298-81-7

Element: methoxypsoralen methoxsalen

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C-S » Chemicals » methoxsalen-methoxypsoralen-PX71904

Identification

Methoxsalen (8-Methoxypsoralen)

CAS:

298-81-7

EINECS:

206-066-9

Molecular Formula:

C₁₂H₈O₄

MDL:

MFCD00005009

SMILES:

COC1=C2C(=CC3=C1OC=C3)C=CC(=O)O2

Synonym:

ammodin ; dermox ; 8-mp ; 8-mop ; puvalen ; metoxin ; uvadex ; vitpso ; puvamet ; meloxine

Description

Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). As a member of the foranocoumarins, 8-Methoxypsoralen has shown more potency than 5-MOP, 5-OH-P , DH-8-MOP and psoralen in the inhibiton of CYP2B1 (cytochrome P-450 2B1). Methoxsalen has been shown to completely inhibit the metabolism of nicotine in vitro. The compound has been observed to inhibit the metabolism of theophylline, caffeine (sc-202514), hexobarbital and phenytoin (sc-210385).

Suppliers

Santa Cruz Biotechnology, Inc.

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Prices & Availability

Data is processed

Properties for Methoxsalen (8-Methoxypsoralen)

Molecular Weight:

216.19 g·mol−1

Density:

1.54 g/cm³

Melting point:

148-150 °C(lit.)

Boiling point:

415° C

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

GHS08
Health hazard

Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A, 1B, 2
Carcinogenicity, categories 1A, 1B, 2
Reproductive toxicity, categories 1A, 1B, 2
Specific target organ toxicity following single exposure, categories 1, 2
Specific target organ toxicity following repeated exposure, categories 1, 2
Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:

R22 - Harmful if swallowed
R34 - Causes burns
R43 - May cause sensitisation by skin contact
R45 - May cause cancer
R46 - May cause inheritable genetic damage

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use

Hazard Symbols:

Xn, T

Storage temperature :

-20 °C Freezer, Under Inert Atmosphere

RID/ADR certification :

3216

Alternative Distributors of [Methoxsalen (8-Methoxypsoralen)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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