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Methotrexate(N-(4-(((2,4-Diamino-6-Pteridinyl)Methylamino)Benzoyl)-L-Glutamic Acid)

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Formula: C20H22N8O5
CAS: 59-05-2
search Element: methotrexate methylamino pteridinyl glutamic benzoyl diamino acid
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Identification

Structural Formula
Methotrexate(N-(4-(((2,4-Diamino-6-Pteridinyl)Methylamino)Benzoyl)-L-Glutamic Acid)
CAS:
59-05-2
EINECS:
200-413-8
Molecular Formula:
C20H22N8O5
MDL:
MFCD00150847
Synonym:
x 133 ; mtx ; nsc-740 ; mexate ; r9985 ; nsc740 ; r 9985 ; hdmtx ; trexall ; nsc 740




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Properties for Methotrexate(N-(4-(((2,4-Diamino-6-Pteridinyl)Methylamino)Benzoyl)-L-Glutamic Acid)

Molecular Weight:
454.44 g·mol−1
Density:
1.54 g/cm3 (Predicted)
Melting point:
195 °C
Solubility:
H2O: insoluble
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Hazard Statements

GHS06

GHS06
Toxic
  • Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3
GHS08

GHS08
Health hazard
  • Respiratory sensitization, category 1
  • Germ cell mutagenicity, categories 1A, 1B, 2
  • Carcinogenicity, categories 1A, 1B, 2
  • Reproductive toxicity, categories 1A, 1B, 2
  • Specific target organ toxicity following single exposure, categories 1, 2
  • Specific target organ toxicity following repeated exposure, categories 1, 2
  • Aspiration hazard, categories 1, 2

Safety & Transport Information

Risk Codes:
R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R36/38 - Irritating to eyes and skin
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R46 - May cause inheritable genetic damage
R61 - May cause harm to the unborn child
Safety Codes:
S16 - Keep away from sources of ignition - No smoking
S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
Hazard Classes:
6.1(b)
Hazard Symbols:
T, F
Hazard symbol T Hazard symbol F
Storage temperature :
-20°C
RID/ADR certification :
UN 2811 6.1 / PG 3
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Alternative Distributors of [Methotrexate(N-(4-(((2,4-Diamino-6-Pteridinyl)Methylamino)Benzoyl)-L-Glutamic Acid)]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

TCI Europe NV | Taizhou Huading Chemical Co., Ltd. | ShangHai Biochempartner Co., Ltd. | Hangzhou Hysen Pharma Co., Ltd. | East Chemical Industry Co., Ltd. | Zhejiang Kaili Industrial Co., Ltd. | Pharmfar Co., Ltd. | Aopharm | Hangzhou Ocean Chemical Co., Ltd. | Sunbow Biotech Ltd. | Finetech Industry Limited | Clearsynth Canada INC. | Wanko Chemical Co., Ltd. | Haihang Industry Co., Ltd.

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