Melatonin | CAS 73-31-4 | Chemical-Suppliers

Element: melatonin

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C-S » Chemicals » melatonin-PX69567

Identification

Melatonin

CAS:

73-31-4

EINECS:

200-797-7

Molecular Formula:

C₁₃H₁₆N₂O₂

MDL:

MFCD00005655

SMILES:

COC1=CC2=C(NC=C2CCNC(C)=O)C=C1

Synonym:

mlt ; melovine ; melatonin ; mlklak ; circadin ; melatonine ; primex ; mlk7 ; melotonin ; mlt1

Description

Melatonin is an indoleamine neurohormone found across plants and animals, produced endogenously from serotonin (5-HT) and secreted in animals as a regulatory signal for synchronization of the circadian rhythm and the sleep-wake cycle. The melatonin receptor system, consisting of the MEL-1A-R, MEL-1B-R, and MT3 subtypes, demonstrates particular plasticity and modularity - antagonists such as Luzindole and 2-Phenylmelatonin show modification of systemic responses to the Melatonin signal without impeding activation of the receptors by Melatonin. Powerful antioxidant activity is associated with Melatonin, and it is known to provide protection to lipids, proteins, and DNA against oxidative damage. Several antioxidant enzymes are shown to be upregulated by Melatonin, including glutathione peroxidase, superoxide dismutases, and catalase. Melatonin also scavenges free radicals as a terminal antioxidant, reacting to generate stable end products and terminate radical chain reactions. Free movement through the blood-brain barrier positions Melatonin as a particularly significant endogenous antioxidant. Melatonin is a rat NOS1 (nNOS) inhibitor. Melatonin is an activator of MEL-1A-R and MEL-1B-R.

Suppliers

XD BIOCHEMS Ltd

XB135405

Wuhan PharmChem Co., LTD.

WP225675

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI6212484

Shandong SanYoung Industry Co., Ltd

SSI3151260

Chengdu Pufeide Biotech. Co., Ltd

CPB2971188

Shandong Ench Chemical Co.,Ltd

SECC2701350

New Natural Biotechnology Co.,Ltd.

NNBC3061530

Nantong Xindao Biotech Ltd

NXB234936

Chemlyte Solutions

CS162486

Shandong Minglang Chemical Co., Ltd

SMC3151260

H&Z Industry Co.,Ltd

HIC180720

Autech Industry Co.,Limited

AIC243972

Ambeed, Inc.

A204285

Symrise BioActives GmbH

SB207621

Indofine Chemical Co, Inc.

025638

Helm U.S. Corporation

HUC189756

AIDP, Inc.

A90180

Suan Farma, Inc

SFI135540

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT4592295

Qingdao Hong Jin Chemical Co., Ltd.

QHJC3151575

ICC Chemical Corporation

ICC216864

CellMark AB

CA99297

Arcadia Biotechnology

AB189567

Intatrade Chemicals GmbH

PS05950

X´ian Taicheng Chem Co., Ltd

XTC2611044

Caesar & Loretz GmbH

CL180540

Xiamen Equation Chemical Co.,Ltd

XECC2881440

Sancai Industry Co.,Ltd.

SIC216864

Arakato Development Ltd

AD207621

Aecochem Corp.

AC126378

CSNpharm, Inc.

CSN11710

Merck Schuchardt OHG

MSO180720

Hangzhou Keying Chem Co., Ltd.

HKC2701080

Hangzhou Lingrui Chemical Co., Ltd.

HLC3151260

scienTEST - bioKEMIX GmbH

S-B225900

Finetech Industry Limited

FIL225900

Simagchem Corporation

SC189567

Xingrui Industry Co., Limited

XIL2611044

Zehao Industry Co., Ltd.

ZI216648

BOC Sciences

BS108324

Amadis Chemical Company Limited

ACCL2791395

Leap Chem Co., Ltd

LC162486

Santa Cruz Biotechnology, Inc.

207848

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Angene International Limited

AGN-PC-00ANBS

Prices & Availability

Data is processed

Properties for Melatonin

Molecular Weight:

232.28 g·mol−1

Density:

1.18 g/cm³ (Predicted)

Melting point:

116.5-118 °C(lit.)

Boiling point:

512.83° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (0.1 mg/ml), ethanol (8 mg/ml), benzene, chloroform, methanol, DMSO (50 mM), toluene, and dilute aqueous acid, and very slightly soluble in petroleum ether.

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
R60 - May impair fertility

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S24/25 - Avoid contact with skin and eyes
S36/37 - Wear suitable protective clothing and gloves
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)
S53 - Avoid exposure - obtain special instructions before use
S7 - Keep container tightly closed

Hazard Symbols:

T, F

Storage temperature :

-15°C

Alternative Distributors of [Melatonin]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified