IB-MECA | CAS 152918-18-8 | Chemical-Suppliers

Element: meca

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C-S » Chemicals » meca-PX58084

Identification

IB-MECA

CAS:

152918-18-8

EINECS:

Molecular Formula:

C₁₈H₁₉ I N₆ O₄

MDL:

MFCD00671785

SMILES:

CNC(=O)[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3NCC4=CC(=CC=C4)I)O)O

Synonym:

1-deoxy-1-[6-[((3-iodophenyl)methyl)amino]-9h-purin-9-yl]-n-methyl-β-d-ribofuranuronamide ; cf-101 ; b-d-ribofuranuronamide, 1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9h-purin-9-yl]-n-methyl- ; n6-(3-iodobenzyl)ado-5'n-methyluronamide ; 1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9h-purin-9-yl]-n-methyl-beta-d-ribofuranuron-amide ; ib-meca selective a3 adenosin ; n(6)-(3-iodobenzyl)-5'-n-methylcarboxamidoadenosine ; ib-meca ; n6-(3-iodobenzyl)adenosine-5'-n-methyluronamide ; cf101 ; b-d-ribofuranuronamide,1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9h-purin-9-yl]-n-methyl- ; n6-(3-iodo-benzyl)adenosine-5'-n-methyluronamide ; selepressin

Description

IB-MECA has been shown to act as a potent and selective Adenosine A3-R agonist with K_i values of 1.1, 54 and 56 nM for Adenosine A3-R, Adenosine A1-R and Adenosine A2A-R, respectively. This compound has demonstrated cardioprotective activity.