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3-MATIDA

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Formula: C8H9NO4S
CAS: 518357-51-2
search Element: matida

Identification

Structural Formula
3-MATIDA
CAS:
518357-51-2
EINECS:
Molecular Formula:
C8H9NO4S
MDL:
SMILES:
CC1=C(SC(=C1)C(=O)O)C(C(=O)O)N
Synonym:
alpha-amino-5-carboxy-3-methyl-2-thiopheneacetic acid ; 3-matida ; α-amino-5-carboxy-3-methyl-2-thiopheneaceticacid ; alpha-amino-5-carboxy-3-methyl-2-thiopheneacetic acid


Description

3-MATIDA is a potent metabotropic glutamate receptor 1(mGluR-1) antagonist (IC50 = 6.3 μM at rat mGluR-1a). Displays ≥ 40-fold selectivity over other receptors: mGluR-5, mGluR-2, mGluR-4 (mGluR-4a) (IC50 > 300 μM), NMDA and GluR (AMPA) (IC50 = 250 μM). 3-MATIDA has been found to act as a neuroprotectant in cultured murine cortical cells and rat hippocampal slice cultures in vitro.


Suppliers

Santa Cruz Biotechnology, Inc.
203470
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Properties for 3-MATIDA

Molecular Weight:
215.23 g·mol−1
Solubility:
Soluble in 1eq. NaOH (100 mM), and DMSO (50 mM).
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Safety & Transport Information

Storage temperature :
Store at +4 °C
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Alternative Distributors of [3-MATIDA]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

BOC Sciences

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