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Masitinib

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Formula: C28H30N6OS
CAS: 790299-79-5
search Element: masitinib
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Identification

Structural Formula
Masitinib
CAS:
790299-79-5
EINECS:
Molecular Formula:
C28H30N6OS
MDL:
SMILES:
CN1CCN(CC2=CC=C(C=C2)C(=O)NC2=CC(NC3=NC(=CS3)C3=CC=CN=C3)=C(C)C=C2)CC1
Synonym:
ab1010 ; masatinib ; masivet ; mastinib ; ab 1010 ; masitinib api ; masitinib(ab1010) ; ab-1010 ; masitinib ; n-(4-methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benz


Description

Masitinib (AB1010) is a tyrosine kinase, c-Kit, PDGFR, FGFR3, and FAK pathway inhibitor with IC50 of 150 ± 80, 200 ± 40 nM for KIT tyrosine phosphorylation and the recombinant wild-type KIT. Masitinib can enhance the antiproliferative effects of gemcitabine (GEM) in pancreatic cancer cells. Masitinib potently inhibits KIT with activating mutations in the juxtamembrane domain.


Suppliers

Lori Industry Co., Ltd
LI198594
+
H&Z Industry Co.,Ltd
HIC180720
+
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI6212484
+
Aea.ltd
A63126
+
Create Chemical Co., Ltd.
CC225675
+
Chemlyte Solutions
CS162486
+
Hangzhou Lingrui Chemical Co., Ltd.
HLC3151260
+
Pharmacore Co., Limited
PL207621
AK Scientific, Inc.
AS171513
+
BOC Sciences
BS108324
+
Leap Chem Co., Ltd
LC162486
+
Santa Cruz Biotechnology, Inc.
211777
Santa Cruz Biotechnology, Inc.
sc-211777
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CAS equal suppliers

AB1010
Aea.ltd
A4284
Mastinib
Excenen Pharmatech Co., Ltd.
EX-A080

Prices & Availability




Data is processed


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Properties for Masitinib

Molecular Weight:
498.64 g·mol−1
Melting point:
90-95 °C C
Solubility:
Chloroform, DMSO, Methanol
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Safety & Transport Information

Storage temperature :
Refrigerator
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Alternative Distributors of [Masitinib]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Evershine Chemical Co.,Ltd. | Chemwill Asia Co.,Limited | ShangHai Biochempartner Co., Ltd. | Unispec Chemicals Co. | Suzhou Rovathin Pharmatech Co., Ltd | U-Chemo Holding Co., Limited | AOKBIO Co., Ltd. | Jinan Great Chemical Co., Ltd. | Bichem Lab Co., Ltd. | East Chemical Industry Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Watson International Ltd | BOC Sciences | Xiamen Hisunny Chemical Co., Ltd. | Sino Rarechem Labs Co. Ltd. | Gihi Chemicals Co., Limited

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Downloads

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MSDS:
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