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7(S)-Maresin 1

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Formula: C22H32O4
CAS: 1268720-66-6
search Element: maresin

Identification

Structural Formula
7(S)-Maresin 1
CAS:
1268720-66-6
EINECS:
Molecular Formula:
C22H32O4
MDL:
SMILES:
C(CC)=CCC=CC[C@H](C=CC=CC=C[C@H](CC=CCCC(=O)O)O[H])O[H]
Synonym:


Description

Docosahexaenoic acid (DHA) is an ω-3 fatty acid that is abundant in the brain and the retina and is known to be important in early development. Maresin 1 (7(R)-MaR1) is a 7,14-DHA formed from 14S-hydroperoxy DHA supplied exogenously to resident peritoneal murine macrophages activated with zymosan A. It potently reduces infiltration of neutrophils into the murine peritoneum in zymosan A-induced peritonitis when given intravenously (0.2 ng) and significantly increases phagocytosis of FITC-labeled zymosan A by isolated mouse macrophages (0.1-100 nM). 7(S)-MaR1 is an epimer of the active 7(R)-MaR1.


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Santa Cruz Biotechnology, Inc.
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Properties for 7(S)-Maresin 1

Molecular Weight:
360.5 g·mol−1
Solubility:
Soluble in DMSO (~50 mg/ml), DMF (~50 mg/ml), and PBS,pH 7.2 (~0.05 mg/ml).
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Alternative Distributors of [7(S)-Maresin 1]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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MSDS:
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