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(+)-MK 801 maleate

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Formula: C20H19NO4
CAS: 77086-22-7
search Element: maleate

Identification

Structural Formula
(+)-MK 801 maleate
CAS:
77086-22-7
EINECS:
278-614-5
Molecular Formula:
C20H19NO4
MDL:
MFCD00082465
SMILES:
C[C@@]12C3=CC=CC=C3C[C@@H](N1)C4=CC=CC=C24.C(=CC(=O)O)C(=O)O
Synonym:
(+)-mk-801 hydrogen maleate (dizocilpine maleate) ; [5r,(-)]-10,11-dihydro-5-methyl-5h-dibenzo[a,d]cyclohepten-5β,10β-imine ; (+)mk801/mk801/mk-801 ; mk801 ; (-)-mk-801 maleate ; dizocipine maleate ; [5r,10s,(-)]-10,11-dihydro-5-methyl-5h-dibenzo[a,d]cyclohepten-5β,10β-imine ; dizocilpine hydrogen maleate ; [5r,10s,(-)]-10,11-dihydro-5-methyl-5h-dibenzo[a,d]cyclohepten-5,10-imine ; (+)-mk-801·maleic acid


Description

(+)-MK 801 Maleate is a selective and non-competitive antagonist of the NMDA receptor. (+)-MK 801 is described to interact at the NMDA-associated ion channel, preventing Ca2+ flux and blocking NMDA-induced depolarizations. (+)-MK 801 demonstrates potent neuroprotective effects against excitotoxic insult, showing substantial protection against neuron loss produced by NMDA and quinolinic acid introduction.


Suppliers

CSNpharm, Inc.
CSN13883
Santa Cruz Biotechnology, Inc.
203137
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Prices & Availability




Data is processed


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Properties for (+)-MK 801 maleate

Molecular Weight:
337.37 g·mol−1
Melting point:
209-210° C
Solubility:
DMSO: >20 mg/mL
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Safety & Transport Information

Safety Codes:
S22 - Do not breathe dust
S24/25 - Avoid contact with skin and eyes
Storage temperature :
Store at RT
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Alternative Distributors of [(+)-MK 801 maleate]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Abcam Biochemicals plc (formaly Ascent Scientific Ltd.) | BOC Sciences

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MSDS:
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