Madecassic acid | CAS 18449-41-7

Element: madecassic acid

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C-S » Chemicals » madecassic-acid-PX1212256

Identification

Madecassic acid

CAS:

18449-41-7

EINECS:

Molecular Formula:

C₃₀H₄₈O₆

MDL:

MFCD00895441

SMILES:

C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(C[C@H]([C@@H]5[C@@]4(C[C@H]([C@@H]([C@@]5(C)CO)O)O)C)O)C)[C@@H]2[C@H]1C)C)C(=O)O

Synonym:

madecassic acid(p) ; madecassic acid, from centella asiatica ; 6beta-hydroxyasiatic acid ; urs-12-en-28-oic acid, 2,3,6,23-tetrahydroxy-, (2.alpha.,3.beta.,4.alpha.,6.beta.)- ; madecassic acid ; (2alpha,3beta,4alpha,6beta)-2,3,6,23-tetrahydroxy-urs-12-en-28-oic acid ; madecasoside ; 6-hydroxyasiatic acid ; hydroxy asiaticoside ; 2α,3β,6β,23-tetrahydroxyurs-12-en-28-oic acid

Description

Madecassic acid has been investigated for stimulating collagen synthesis. Madecassic acid acts as a downregulator of NF-kappaB activation in RAW 264.7 macrophage cells which inhibits iNOS, COX-2, TNF-alpha, IL-1beta, and IL-6 and results in a reduction in inflammation.

Suppliers

H&Z Industry Co.,Ltd

HIC6002400

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI20708280

Chemlyte Solutions

CS5401620

New Natural Biotechnology Co.,Ltd.

NNBC10205100

Autech Industry Co.,Limited

AIC8103240

Chengdu Pufeide Biotech. Co., Ltd

CPB9903960

Indofine Chemical Co, Inc.

020029

Evonik ( formerly Wilshire Technologies, Inc. )

E14405760

Hangzhou Keying Chem Co., Ltd.

HKC9003600

Pharmacore Co., Limited

PL6902070

Acinopeptide Co., Ltd.

A6601320

Leap Chem Co., Ltd

LC5401620

Santa Cruz Biotechnology, Inc.

391157

Dayang Chem (Hangzhou) Co.,Ltd.

DC9303720

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CAS equal suppliers

(2a,3 b, 4a, 6b)-2,3,6, 23-Tetrahydroxy-URS-12-en-28-oic acid

Xingrui Industry Co., Limited

XIL1592163684

Prices & Availability

Data is processed

Properties for Madecassic acid

Molecular Weight:

504.7 g·mol−1

Density:

~1.2 g/cm³ (Predicted)

Melting point:

270 °C (dec.)

Boiling point:

641.7 °C

Solubility:

Soluble in DMSO, and methanol.

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Hazard Symbols:

Alternative Distributors of [Madecassic acid]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

Downloads

Mol File:

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MSDS:

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