Loxoribine | CAS 121288-39-9 | Chemical-Suppliers

Element: loxoribine

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C-S » Chemicals » loxoribine-PX75444

Identification

Loxoribine

CAS:

121288-39-9

EINECS:

Molecular Formula:

C₁₃H₁₇N₅O₆

MDL:

MFCD00867591

SMILES:

C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)O

Synonym:

guanosine,7,8-dihydro-8-oxo-7-(2-propen-1-yl)- ; 7,8-dihydro-8-oxo-7-(2-propenyl)guanosine ; 9-[(4s,2r,3r,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-amino-7-prop-2-enyl-1,7-dihydropurine-6,8-dione ; 7-allyl-2-amino-9-(3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-7,9-dihydro-1h-purine-6,8-dione ; 2-amino-9-[(2r,3r,4s,5r)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-7-prop-2-enyl-3h-purine-6,8-dione ; 7-allyl-8-oxoguanosine ; 7-allyl-2-amino-9-beta-d-ribofuranosylpurine-6,8(1h,9h)-dione ; rwj 21757 ; 7-allyl-7,8-dihydro-8-oxoguanosine (loxoribine) ; guanosine, 7,8-dihydro-8-oxo-7-(2-propenyl)- ; 7-allyl-7 8-dihydro-8-oxoguanosine 95 ; 7-allyl-2-amino-9b-d-ribofuranosylpurine-6,8(1h,9h)-dione ; unii-9cas0v66oi ; 7-allyl-7,8-dihydro-8-oxoguanosine 95% ; loxoribine ; loxoribinum

Description

Loxoribine is a selective agonist for TLR7 (Toll-like receptor 7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2. Loxoribine is a very potent immunostimulatory compound that increases cytokine production and possesses antitumor and antiviral properties.

Suppliers

General Intermediates of Canada, Inc.

GIOC3701850

Santa Cruz Biotechnology, Inc.

203118

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CAS equal suppliers

7-Allyl-8-oxoguanosine

Leap Chem Co., Ltd

LC7922376

7-Allyl-7,8-dihydro-8-oxoguanosine

General Intermediates of Canada, Inc.

GIOC377418870

7-Allyl-7,8-dihydro-8-oxoguanosine

Amadis Chemical Company Limited

ACCL316215810

Guanosine, 7,8-dihydro-8-oxo-7-(2-propenyl)-

Angene International Limited

AGN-PC-0O0AZ6

Prices & Availability

Data is processed

Properties for Loxoribine

Molecular Weight:

339.306 g·mol−1

Density:

1.92 g/cm3

Melting point:

227-230 °C(lit.)

Boiling point:

591.8 °C at 760 mmHg

Flash point:

311.7 °C

Solubility:

Soluble in DMSO (30 mg/ml), water (10 mg/ml), water:acetonitrile (1:1) (20 mg/ml), and water:methanol (1:1) (10 mg/ml).

Safety & Transport Information

Storage temperature :

Desiccate at +4 °C

Alternative Distributors of [Loxoribine]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

Downloads

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MSDS:

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