Losartan Potassium | CAS 124750-99-8

Element: potassium losartan

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C-S » Chemicals » losartan-potassium-PX76889

Identification

Losartan Potassium

CAS:

124750-99-8

EINECS:

Molecular Formula:

C₂₂H₂₂ClN₆OK

MDL:

MFCD02092704

SMILES:

CCCCC1=NC(=C(N1CC2=CC=C(C=C2)C3=CC=CC=C3C4=NN=N[N-]4)CO)Cl.[K+]

Synonym:

l-158086 ; mk 954 ; cozaar ; mk-0954 ; dupont753 ; losartan potassium ; aradois ; dup 753 ; thanolpotassium ; mk-95

Description

Losartan Potassium is a specific antagonist of the angiotensin II receptor subtype AT1. Antagonism of the AT1 receptor and interference of association between AT1 and angiotensin II produces vasodilation and reduction of hypertension. This antagonism has other downstream effects, including a correlated antagonism of the thromboxane A2 receptor, inhibition of platelet aggregation, and induction of peroxisome proliferator-actived receptor gamma (PPARγ) activity.

Suppliers

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI24849936

Shandong Ench Chemical Co.,Ltd

SECC10805400

H&Z Industry Co.,Ltd

HIC7202880

Shandong SanYoung Industry Co., Ltd

SSI12605040

Nantong Xindao Biotech Ltd

NXB9363744

XD BIOCHEMS Ltd

XB5401620

Chemlyte Solutions

CS6481944

Ambeed, Inc.

A561984

Hangzhou Cherry Pharmaceutical Technology Co., Ltd.

HCPT18369180

Eastar Chemical Corporation

ECC9723888

Arcadia Biotechnology

AB7562268

Sinogreat Enterprise Ltd.

SE9002700

Xiamen Equation Chemical Co.,Ltd

XECC11525760

Sancai Industry Co.,Ltd.

SIC8643456

Arakato Development Ltd

AD8282484

Aecochem Corp.

AC5041512

CSNpharm, Inc.

CSN12515

Hangzhou Lingrui Chemical Co., Ltd.

HLC12605040

Wanko Chemical Co., Ltd.

WC8642592

Sigma-Aldrich International GmbH

SI11523456

scienTEST - bioKEMIX GmbH

S-B9003600

Finetech Industry Limited

FIL9003600

Carbone Scientific Co., Ltd.

CS10083024

CM Fine Chemicals

CFC6122448

AK Scientific, Inc.

AS6842052

Xingrui Industry Co., Limited

XIL10444176

BOC Sciences

BS4321296

Leap Chem Co., Ltd

LC6481944

Santa Cruz Biotechnology, Inc.

204796

Dayang Chem (Hangzhou) Co.,Ltd.

DC11164464

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CAS equal suppliers

Losartan Potassium

Jiwan Pharmaceutical Technology Co., Ltd.

JPT16406560

Losartan potassium salt

Molekula

57826018

Losartan potassium, Pharma

Salsbury Chemicals, Inc.

SC18725616

2-n-Butyl-4-chloro-5-(hydroxymethyl)-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole potassium

Eastar Chemical Corporation

ECC38556154224

2-n-Butyl-4-chloro-5-(hydroxymethyl)-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]imidazole potassium

Hangzhou J&H Chemical Co., Ltd.

HJC44268177072

(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol, potassium salt

BLD Pharmatech Ltd

BP34884104652

Prices & Availability

Data is processed

Properties for Losartan Potassium

Molecular Weight:

462.01 g·mol−1

Melting point:

263-265 °C

Boiling point:

682° C at 760 mmHg (Predicted)

Solubility:

Soluble in water (>500 mg/ml), PBS (pH 7.2) (≥10 mg/ml), ethanol (≥20 mg/ml), DMSO (100 mM), and DMF (≥20 mg/ml).

Hazard Statements

GHS03
Harmful

Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, categories 2, 3
Eye irritation, category 2A
Skin sensitization, category 1
Specific target organ toxicity following single exposure, category 3
- Respiratory tract irritation
- Narcotic effects

Not used

with the "skull and crossbones" pictogram
for skin or eye irritation if:
the "corrosion" pictogram also appears
the "health hazard" pictogram is used to indicate respiratory sensitization

Safety & Transport Information

Risk Codes:

R36/37/38 - Irritating to eyes, respiratory system and skin

Safety Codes:

S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection

Hazard Symbols:

Storage temperature :

Desiccate at RT

Alternative Distributors of [Losartan Potassium]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified