LOE 908 hydrochloride | CAS 149759-26-2

Element: hydrochloride

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C-S » Chemicals » loe-hydrochloride-PX82305

Identification

LOE 908 hydrochloride

CAS:

149759-26-2

EINECS:

Molecular Formula:

C₄₁H₄₈N₂O₉.ClH

MDL:

SMILES:

COC1=C(C(=C(C=C1)CCN(CCC2=C(C(=C(C=C2)OC)OC)OC)C(=O)C(C3=CC=CC=C3)C4=NCCC5=CC(=C(C=C54)OC)OC)OC)OC.Cl

Synonym:

3,4-dihydro-6,7-dimethoxy-α-phenyl-n,n-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-1-isoquinolineacetamidehydrochloride ; pinokalant ; loe 908 hydrochloride ; loe 908 ; 1-isoquinolineacetamide,3,4-dihydro-6,7-dimethoxy-a-phenyl-n,n-bis[2-(2,3,4-trimethoxyphenyl)ethyl]- ; 1-isoquinolineacetamide,3,4-dihydro-6,7-dimethoxy-a-phenyl-n,n-bis[2-(2,3,4-trimethoxyphenyl)ethyl]-, (?Ã )-

Description

LOE 908 hydrochloride is a broad spectrum cation channel blocker. This can inhibit several cation channeles: store-operated calcium channels, voltage-operated calcium channels, non-selective cation channels, AMPA, NMDA, Na, and K channels. Neuroprotective.