Lobeline hydrochloride | CAS 134-63-4

Element: hydrochloride lobeline

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C-S » Chemicals » lobeline-hydrochloride-PX80284

Identification

Lobeline hydrochloride

CAS:

134-63-4

EINECS:

205-150-2

Molecular Formula:

C₂₂H₂₇NO₂.HCl

MDL:

MFCD00082455

SMILES:

CN1[C@@H](CCC[C@@H]1CC(=O)C2=CC=CC=C2)C[C@@H](C3=CC=CC=C3)O.Cl

Synonym:

lobeline hcl, a- ; (-)-id ; einecs 205-150-2 ; alpha-lobelin hcl ; a-lobeline hcl ; (-)-lobeline hcl ; lobeline hydrochloride ; lobeline hcl salt ; a-lobeline ; lobelinhydrochloride

Description

Lobeline hydrochloride is the hydrochloride salt preparation of Lobeline, a potent agonist of the AChR (nicotinic acetylcholine receptor). Lobeline is demonstrated to increase ⁸⁶Rb⁺ efflux at lower concentrations and to reduce ⁸⁶Rb⁺ efflux at higher concentrations, suggesting a differential receptor subtype selectivity from nicotine and agonism through a non-nicotinic mechanism. Lobeline is also described to inhibit dopamine uptake into synaptic vesicles.

Suppliers

Ambeed, Inc.

A561413

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI303612144

Pugh & Co International S.A. - N.V.

PIS-N15409240

Boehringer Ingelheim GmbH

BI11003300

Simagchem Corporation

SC9242772

Xingrui Industry Co., Limited

XIL12765104

Santa Cruz Biotechnology, Inc.

203114

Dayang Chem (Hangzhou) Co.,Ltd.

DC13645456

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Prices & Availability

Data is processed

Properties for Lobeline hydrochloride

Molecular Weight:

373.92 g·mol−1

Melting point:

183-185 °C (dec.)(lit.)

Boiling point:

485.6° C at 760 mmHg (Predicted)

Solubility:

H₂O: 25 mg/mL

Hazard Statements

GHS06
Toxic

Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:

R23/25 - Toxic by inhalation and if swallowed

Safety Codes:

S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

6.1(b)

Hazard Symbols:

Storage temperature :

Store at RT

RID/ADR certification :

UN 1544 6.1 / PG 3

Alternative Distributors of [Lobeline hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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MSDS:

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