5(S),6(R)-Lipoxin A4 methyl ester | CAS 97643-35-1

Element: lipoxin methyl ester

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Identification

5(S),6(R)-Lipoxin A4 methyl ester

CAS:

97643-35-1

EINECS:

Molecular Formula:

C₂₁H₃₄ O₅

MDL:

MFCD05863930

SMILES:

CCCCC[C@@H](/C=C/C=CC=CC=C[C@H]([C@H](CCCC(=O)OC)O)O)O

Synonym:

7,9,11,13-eicosatetraenoic acid, 5,6,15-trihydroxy-, methyl ester,[5s-(5r*,6s*,7e,9e,11z,13e,15r*)]- ; (6r)-lipoxin a methyl ester ; 5(s),6(r),15(s)-trihete methyl ester ; 5(s),6(r)-lipoxin a4 methyl ester ; 7,9,11,13-eicosatetraenoicacid, 5,6,15-trihydroxy-, methyl ester, (5s,6r,7e,9e,11z,13e,15s)- ; 7,9,11,13-eicosatetraenoicacid, 5,6,15-trihydroxy-, methyl ester, (5r,6s,7e,9e,11z,13e,15r)- (9ci) ; 5s,6r,15s-trihydroxy-7e,9e,11z,13e-eicosatetraenoic acid, methyl ester

Description

5(S),6(R)-Lipoxin A4 methyl ester is a more lipid soluble, prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes. 5(S),6(R)-LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM. 5(S),6(R)-LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.

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Properties for 5(S),6(R)-Lipoxin A4 methyl ester

Molecular Weight:

366.49 g·mol−1

Boiling point:

78° C

Solubility:

Soluble in water (1 mg/ml at 25° C), PBS pH7.2 (~1 mg/ml), ethanol, DMSO, and DMF.

Safety & Transport Information

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Alternative Distributors of [5(S),6(R)-Lipoxin A4 methyl ester]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.

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