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Lipoprotein Lipase Activator

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Formula: C19H20BrN2O4P
CAS: 133208-93-2

Identification

Structural Formula
Lipoprotein Lipase Activator
CAS:
133208-93-2
EINECS:
Molecular Formula:
C19H20BrN2O4P
MDL:
MFCD00897807
SMILES:
CCOP(=O)(CC1=CC=C(C=C1)C(=O)NC2=C(C=C(C=C2)Br)C#N)OCC
Synonym:
4-Diethoxyphosphorylmethyl-N-(4-bromo-2-cyanophenyl)benzamide


Description

Lipoprotein Lipase Activator is a cell-permeable benzylphosphonate derivative that selectively induces lipoprotein lipase (LPL) mRNA and protein levels, but does not exhibit PPARα or PPARγ agonistic activities. Lipoprotein Lipase Activator lowers serum lipid levels and plasma triglycerides with concomitant elevation in high-density lipoprotein cholesterol (HDL-C) in animal models. Lipoprotein Lipase Activator also induces fatty acid oxidation related enzymes, lowers free fatty acids (FFA), and minimizes fat accumulation. Also reported to suppress the plasma levels of TNF-a and COX-2 and displays anti-tumor properties.


Suppliers

Santa Cruz Biotechnology, Inc.
204059
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CAS equal suppliers

diethyl 4-[(4-bromo-2-cyanoanilino)carbonyl]benzylphosphonate
Key Organics Limited
SS-3273

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Properties for Lipoprotein Lipase Activator

Molecular Weight:
451.25 g·mol−1
Density:
1.44 g/cm3 (Predicted)
Melting point:
90.27° C (Predicted)
Boiling point:
512.47° C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (≥20 mg/ml).
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Safety & Transport Information

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Alternative Distributors of [Lipoprotein Lipase Activator]

Producers or manufacturers change the product range from time to time. Currently there are no other manufacturers known.
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