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Licochalcone A

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Formula: C21H22O4
CAS: 58749-22-7
search Element: licochalcone

Identification

Structural Formula
Licochalcone A
CAS:
58749-22-7
EINECS:
Molecular Formula:
C21H22O4
MDL:
MFCD01417903
SMILES:
CC(C)(C=C)C1=C(C=C(C(=C1)/C=C/C(=O)C2=CC=C(C=C2)O)OC)O
Synonym:
(e)-3-[5-(1,1-dimethyl-2-propenyl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-2-propen-1-one ; 2-propen-1-one, 3-[5-(1,1-dimethyl-2-propen-1-yl)-4-hydroxy-2-methoxyphenyl]-1-(4-hydroxyphenyl)-, (2e)- ; licochalcone a, >=98% ; licochalcone-a ; 7-dimethoxycoumarin ; 4',4-dihydroxy-3-α,α-dimethylallyl-6-methoxychalcone


Description

Licochalcone A, Synthetic is an estrogenic flavanoid originally derived from licorice root (Glycyrrhiza glabra). Licochalcone-A has displayed the ability to reduce Bcl-2 protein expression and induce apoptosis in several human cancer cell lines. Licochalcone-A also induces cell differentiation, exhibits antibacterial, antiinflammatory and antitumor activity. It has been reported to interfere with parasite mitochondrial electron transport chain and energy metabolism, and also to inhibitin vitro growth of the human malaria parasite Plasmodium falciparum. There is also evidence that licochalcone-A can regulate rat vascular smooth muscle cell proliferation.


Suppliers

Autech Industry Co.,Limited
AIC7563024
Ambeed, Inc.
A341742
Chengdu Pufeide Biotech. Co., Ltd
CPB9243696
Shandong Ench Chemical Co.,Ltd
SECC8404200
Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)
CI19327728
Indofine Chemical Co, Inc.
06-805
CSNpharm, Inc.
CSN16424
BOC Sciences
BS3361008
Amadis Chemical Company Limited
ACCL8684340
Santa Cruz Biotechnology, Inc.
319884
Dayang Chem (Hangzhou) Co.,Ltd.
DC8683472
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CAS equal suppliers

LICOCHALCONE-A
Acinopeptide Co., Ltd.
A308616
LICOCHALCONE-A
Leap Chem Co., Ltd
LC252756
LICOCHALCONE-A
Skyrun Industrial Co., Ltd.
SI3781134
LICOCHALCONE-A
Pharmacore Co., Limited
PL322966
LICOCHALCONE-A
Hangzhou Lingrui Chemical Co., Ltd.
HLC4901960
Licochalcone-a
ShangHai Biochempartner Co., Ltd.
BCP08941
Licochalcone-A, Synthetic
Santa Cruz Biotechnology, Inc.
sc-319884
(2E)-3-[4-Hydroxy-2-methoxy-5-(2-methylbut-3-en-2-yl)phenyl]-1-(4-hydroxyphenyl)prop-2-en-1-one
BLD Pharmatech Ltd
BP2736082080

Prices & Availability




Data is processed


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Properties for Licochalcone A

Molecular Weight:
338.4 g·mol−1
Density:
~1.2 g/cm3 (Predicted)
Melting point:
198.85 °C (Predicted)
Boiling point:
~532.6 °C at 760 mmHg (Predicted)
Solubility:
Soluble in DMSO (10 mg/mL), and 100% ethanol.
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Safety & Transport Information

Risk Codes:
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
Safety Codes:
S36/37 - Wear suitable protective clothing and gloves
Hazard Symbols:
Xn
Hazard symbol Xn
Storage temperature :
?20 °C
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Alternative Distributors of [Licochalcone A]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

East Chemical Industry Co., Ltd. | Shanghai Tauto Biotech Co., Ltd. | Jinan Great Chemical Co., Ltd. | Shanghai Witofly Chemical Co., Ltd. | Cfm Oskar Tropitzsch GmbH | Chengdu Conut Intl. Co., Ltd. | BOC Sciences

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MSDS:
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