Levamisole Hydrochloride | CAS 16595-80-5

Element: hydrochloride levamisole

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C-S » Chemicals » levamisole-hydrochloride-PX81115

Identification

Levamisole Hydrochloride

CAS:

16595-80-5

EINECS:

240-654-6

Molecular Formula:

C₁₁H₁₂N₂S.HCl

MDL:

MFCD00012675

SMILES:

C1CSC2=N[C@H](CN21)C3=CC=CC=C3.Cl

Synonym:

solaskil ; tramisole ; r-12,564 ; citarinl ; dekaris ; tramisol ; kw-2-le-t ; levadin ; decaris ; levacide

Description

Levamisole Hydrochloride is an immunomodulatory agent which selectively induces apoptosis in human micro-and macro vascular endothelial cells. In vitro studies suggest that Levamisole Hydrochloride has been used to cause cytotoxic effects in several types of tumor cell lines by potentiating the anti-proliferative effect of 5-fluorouracil. As a result of the cytotoxic effect of Levamisole Hydrochloride DNA fragmentation, release of cytochrome c into the cytoplasm, and the activation of caspase-3 has been observed in cells. Alternate studies have shown that Levamisole Hydrochloride can be used to inhibit the growth of Toxocara canis. Levamisole Hydrochloride has also been shown to increase T-lymphocyte function and macrophage chemotaxis in rheumatic disorder cells. Levamisole Hydrochloride is an activator of AChR. Levamisole Hydrochloride is an inhibitor of Alkaline Phosphatase.

Suppliers

H&Z Industry Co.,Ltd

HIC9603840

Chemlyte Solutions

CS8642592

Ambeed, Inc.

A121733

Conscientia Industrial Co., Ltd (Zhejiang Conscientia Pharmaceutical)

CI331213248

Shandong Ench Chemical Co.,Ltd

SECC14407200

Shandong Minglang Chemical Co., Ltd

SMC16806720

X´ian Taicheng Chem Co., Ltd

XTC13925568

Hangzhou Verychem Science & Technology Co., Ltd.

HVST230411520

Xiamen Equation Chemical Co.,Ltd

XECC15367680

Sancai Industry Co.,Ltd.

SIC11524608

Aecochem Corp.

AC6722016

AK Scientific, Inc.

AS9122736

Simagchem Corporation

SC10083024

Xingrui Industry Co., Limited

XIL13925568

Amadis Chemical Company Limited

ACCL14887440

Santa Cruz Biotechnology, Inc.

205730

Dayang Chem (Hangzhou) Co.,Ltd.

DC14885952

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Prices & Availability

Data is processed

Properties for Levamisole Hydrochloride

Molecular Weight:

240.75 g·mol−1

Melting point:

266-267 °C(lit.)

Solubility:

Soluble in water (48 mg/ml), methanol, DMSO (100 mM), and ethanol (<1 mg/ml).

Hazard Statements

GHS06
Toxic

Acute toxicity (oral, dermal, inhalation), categories 1, 2, 3

Safety & Transport Information

Risk Codes:

R11 - Highly flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R23/24/25 - Toxic by inhalation, in contact with skin and if swallowed
R25 - Toxic if swallowed
R39/23/24/25 - Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed

Safety Codes:

S16 - Keep away from sources of ignition - No smoking
S36 - Wear suitable protective clothing
S36/37 - Wear suitable protective clothing and gloves
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
S45 - In case of accident or if you feel unwell seek medical advice immediately (show the label where possible)

Hazard Classes:

6.1(b)

Hazard Symbols:

T, Xn, F

Storage temperature :

0-6°C

RID/ADR certification :

UN 2811 6.1 / PG 3

Alternative Distributors of [Levamisole Hydrochloride]

Producers or manufacturers change the product range from time to time. The following companies
have appeared as suppliers in the past / currently not verified

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